DIPOS: database of interacting proteins in Oryza sativa (original) (raw)

Author affiliations

* Corresponding authors

a Institute of Systems Biology, Shanghai University, Shanghai 200444, China
E-mail: xm_zhao@shu.edu.cn

b School of Communication and Information Engineering, Shanghai University, Shanghai 200444, China

c Monsanto Company, St. Louis, Missouri 63167, USA
E-mail: yongwei.cao@monsanto.com

d Key Laboratory of Systems Biology, Pre-Diabetes Center, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
E-mail: lnchen@staff.shu.edu.cn

e Collaborative Research Center for Innovative Mathematical Modelling, Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan

Abstract

Rice is an important crop throughout the world and is the staple food for about half the world's population. For better breeding and improved production, we need to know the function of rice molecules which facilitate their function through interactions with each other. The database of interacting proteins in Oryza sativa (DIPOS) provides comprehensive information of interacting proteins in rice, where the interactions are predicted using two computational methods, i.e., interologs and domain based methods. DIPOS contains 14 614 067 pairwise interactions among 27 746 proteins, covering about 41% of the whole Oryaza sativa proteome. Furthermore, each interaction is assigned a confidence score which further enables biologists to sort out the important proteins. Biological explanations of pathways and interactions are also provided based on the database. Public access to the DIPOS is available at http://csb.shu.edu.cn/dipos and http://ppi.riceresearch.info.

Graphical abstract: DIPOS: database of interacting proteins in Oryza sativa

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Article information

DOI

https://doi.org/10.1039/C1MB05120B

Article type

Paper

Submitted

27 Mar 2011

Accepted

27 May 2011

First published

29 Jun 2011

Download Citation

Mol. BioSyst., 2011,7, 2615-2621

Permissions

DIPOS: database of interacting proteins in Oryza sativa

A. Sapkota, X. Liu, X. Zhao, Y. Cao, J. Liu, Z. Liu and L. Chen,Mol. BioSyst., 2011, 7, 2615DOI: 10.1039/C1MB05120B

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