N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours (original) (raw)
Alessandri G, Cornaglia Ferraris P and Gullino PM (1997) Angiogenic and angiostatic microenvironment in tumors – role of gangliosides. Acta Oncol36: 383–387 ArticleCAS Google Scholar
Andersson U, Butters TD, Dwek RA and Platt FM (2000) N- butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo. Biochem Pharmacol59: 821–829 ArticleCAS Google Scholar
Bai H and Seyfried TN (1997) Influence of ganglioside GM3 and high density lipoprotein (HDL) on the cohesion of mouse brain tumor cells. J Lipid Res38: 160–172 CAS Google Scholar
Berra B, Colombo I, Monteggia E, Montorfano G, Moretti S, Rapelli S and Sottocornola E (1997) Glycosphingolipid expression in solid tumours and transformed cell lines. Indian J Biochem Biophys34: 170–177 CAS Google Scholar
Brigande JV, Platt FM and Seyfried TN (1998) Inhibition of glycosphingolipid biosynthesis does not impair growth or morphogenesis of the postimplantation mouse embryo. J Neurochem70: 871–882 ArticleCAS Google Scholar
Chang F, Li R and Ladisch S (1997) Shedding of gangliosides by human medulloblastoma cells. Exp Cell Res234: 341–346 ArticleCAS Google Scholar
Cotterchio M and Seyfried TN (1993) The influence of ImuVert, a biological response modifier, on the growth and ganglioside composition of murine neural tumors. Mol Chem Neuropathol20: 163–172 ArticleCAS Google Scholar
Cotterchio M and Seyfried TN (1994) Serum gangliosides in mice with metastatic and non-metastatic brain tumors. J Lipid Res35: 10–14 CAS Google Scholar
Cox T, Lachmann R, Hollak C, Aerts J, van Weely S, Hrebicek M, Platt F, Butters T, Dwek R, Moyses C, Gow I, Elstein D and Zimran A (2000) Novel oral treatment of Gaucher’s disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis. Lancet355: 1481–1485 ArticleCAS Google Scholar
Davis FG, McCarthy BJ, Freels S, Kupelian V and Bondy ML (1999) The conditional probability of survival of patients with primary malignant brain tumors: surveillance, epidemiology, and end results (SEER) data. Cancer85: 485–491 ArticleCAS Google Scholar
Ecsedy JA, Yohe HC, Bergeron AJ and Seyfried TN (1998) Tumor-infiltrating macrophages contribute to the glycosphinglipid composition of brain tumors. J Lipid Res39: 2218–2227 CAS Google Scholar
Ecsedy JA, Holthaus KA, Yohe HC and Seyfried TN (1999) Expression of mouse sialic acid on gangliosides of a human glioma grown as a xenograft in SCID mice. J Neurochem73: 254–259 ArticleCAS Google Scholar
El-Abbadi M and Seyfried TN (1994) Influence of growth environmental on the ganglioside composition of an experimental mouse brain tumor. Mol Chem Neuropathol21: 273–285 ArticleCAS Google Scholar
Fathallah-Shaykh H (1999) New molecular strategies to cure brain tumors. Arch Neurol56: 449–453 ArticleCAS Google Scholar
Fischl MA, Resnick L, Coombs R, Kremer AB, Pottage JC, Jr Fass RJ, Fife KH, Powderly WG, Collier AC, Aspinall RL, Smith SL, Kowalski KG and Wallemark C-B (1994) The safety and efficacy of combination N-butyl-deoxynojirimycin (SC-48334) and zidovudine in patients with HIV-1 infection and 200–500 CD4 cells/mm3. J Acquir Immune Defic Syndr7: 139–147 CAS Google Scholar
Flavin HJ, Wieraszko A and Seyfried TN (1991) Enhanced aspartate release from hippocampal slices of epileptic (El) mice. J Neurochem56: 1007–1011 ArticleCAS Google Scholar
Folch J, Lees M and GH Sloane-Stanley (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem226: 497–509 CAS Google Scholar
Hakomori S (1996) Tumor malignancy defined by aberrant glycosylation and sphingo (glyco) lipid metabolism. Cancer Res56: 5309–5318 CAS Google Scholar
Harbaugh KS and Black PM (1998) Strategies in the surgical management of malignant gliomas. Semin-Surg-Oncol14: 26–33 ArticleCAS Google Scholar
Jeyakumar M, Butters TD, Cortina-Borja M, Hunnam V, Proia RL, Perry VH, Dwek RA and Platt FM (1999) Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin. Proc Natl Acad Sci USA96: 6388–6393 ArticleCAS Google Scholar
Karlsson GB, Butters TD, Dwek RA and Platt FM (1993) Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120. J Biol Chem268: 570–576 CAS Google Scholar
Kemp RB (1968) Effect of the removal of cell surface sialic acids on cell aggregation in vitro. Nature218: 1255–1256 ArticleCAS Google Scholar
Liu YY, Han TY, Giuliano AE and Cabot MC (1999) Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells. J Biol Chem274: 1140–1146 ArticleCAS Google Scholar
Manfredi MG, Lim S, Claffey KP and Seyfried TN (1999) Gangliosides influence angiogenesis in an experimental mouse brain tumor. Cancer Res59: 5392–5397 CAS Google Scholar
Merzak A, Koochekpour S, McCrea S, Roxanis Y and Pilkington GJ (1995) Gangliosides modulate proliferation, migration, and invasiveness of human brain tumor cells in vitro. Mol Chem Neuropathol24: 121–135 ArticleCAS Google Scholar
Platt FM and Butters TD (1995) Inhibitors of glycosphingolipid biosynthesis. Trends Glycosci Glycotech7: 495–511 ArticleCAS Google Scholar
Platt FM and Butters TD (1998) New therapeutic prospects for the glycosphingolipid lysosomal storage diseases. Biochem Pharmacol56: 421–430 ArticleCAS Google Scholar
Platt FM, Neises GR, Dwek RA and Butters TD (1994) N- butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis. J Biol Chem269: 8362–8365 CAS Google Scholar
Platt FM, Neises GR, Reinkensmeier G, Townsend MJ, Perry VH, Proia RL, Winchester B, Dwek RA and Butters TD (1997a) Prevention of lysosomal storage in Tay-Sachs mice treated with N- butyldeoxynojirimycin. Science276: 428–431 ArticleCAS Google Scholar
Platt FM, Reinkensmeier G, Dwek RA and Butters TD (1997b) Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin. J Biol Chem272: 19365–19372 ArticleCAS Google Scholar
Prados MD and Levin V (2000) Biology and treatment of malignant glioma. Semin Oncol27: 1–10 CAS Google Scholar
Radin NS (1999) Chemotherapy by slowing glucosphingolipid synthesis. Biochem Pharmacol57: 589–595 ArticleCAS Google Scholar
Ranes MK, Manfredi MG, El-Abbadi MM, Platt FM and Seyfried TN (2000) N-Butyldeoxynojirmycin reduces growth rate and ganglioside content in mouse brain tumors. Proc Amer Assoc Cancer Res41: 258 Google Scholar
Rubin R, Sutton CH and Zimmerman HM (1968) Experimental ependymoblastoma (fine structure). J Neuropathol Exp Neurol27: 421–438 Article Google Scholar
Sandhoff K and van Echten G (1994) Ganglioside metabolism: enzymology, topology and regulation. Prog Brain Res101: 17–29 ArticleCAS Google Scholar
Schmidt CW (1998) Childhood cancer: A growing problem. Environ Health Perspect106: A18–A23 ArticleCAS Google Scholar
Seyfried TN (2001) Perspectives on brain tumor formation involving macrophages, glia, and neural stem cells. Persp Biol Med, in press
Seyfried TN, Glaser GH and Yu RK (1978) Cerebral, cerebellar, and brain stem gangliosides in mice susceptible to audiogenic seizures. J Neurochem31: 21–27 ArticleCAS Google Scholar
Seyfried TN, Yu RK, Saito M and Albert M (1987) Ganglioside composition of an experimental mouse brain tumor. Cancer Res47: 3538–3542 CAS Google Scholar
Seyfried TN, El-Abbadi M and Roy ML (1992) Ganglioside distribution in murine neural tumors. Mol Chem Neuropathol17: 147–167 ArticleCAS Google Scholar
Seyfried TN, Novikov AM, Irvine RA and Brigande JV (1994) Ganglioside biosynthesis in mouse embroys: sialyltransferase IV and the asialo pathway. J Lipid Res35: 993–1001 CAS Google Scholar
Seyfried TN, El-Abbadi M, Ecsedy JA, Bai HW and Yohe H (1996) Influence of host cell infiltration on the glycolipid content of mouse brain tumors. J Neurochem66: 2026–2033 ArticleCAS Google Scholar
Seyfried TN, El-Abbadi M, Ecsedy JA, Griffin ME and Yohe HC (1998) Ganglioside composition of a mouse brain tumor grown in the severe combined immunodeficiency (SCID) mouse. Mol Chem Neuropathol33: 27–37 ArticleCAS Google Scholar
Shapiro WR (1999) Current therapy for brain tumors: back to the future. Arch Neurol56: 429–432 ArticleCAS Google Scholar
Svennerholm L (1957) Quantitative estimation of sialic acids II. A colorimetric resorcinol-hydrochloric acid method. Biochim Biophys Acta24: 604–611 ArticleCAS Google Scholar
Weindruch R and Walford RL (1988) The retardation of aging and disease by dietary restriction. Thomas: Springfield, IL.
Yu RK and Ledeen RW (1970) Gas–liquid chromatographic assay of lipid-bound sialic acids: measurement of gangliosides in brain of several species. J Lipid Res11: 506–516 CAS Google Scholar
Yung WK, Albright RE, Olson J, Fredericks R, Fink K, Prados MD, Brada M, Spence A, Hohl RJ, Shapiro W, Glantz M, Greenberg H, Selker RG, Vick NA, Rampling R, Friedman H, Phillips P, Bruner J, Yue N, Osoba D, Zaknoen S and Levin VA (2000) A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer83: 588–593 ArticleCAS Google Scholar
Zeng G, Gao L, Birkle S and Yu RK (2000) Suppression of ganglioside GD3 expression in a rat F-11 tumor cell line reduces tumor growth, angiogenesis, and vascular endothelial growth factor production. Cancer Res60: 6670–6676 CAS Google Scholar
Zimmerman HM (1982) Production of brain tumors with aromatic hydrocarbons. Ann N Y Acad Sci381: 320–324 ArticleCAS Google Scholar