Self-Expanding Metal Stents in Benign Biliary Strictures Due to Chronic Pancreatitis (original) (raw)

Endoscopy 2004; 36(5): 381-384
DOI: 10.1055/s-2004-814319

Original Article

© Georg Thieme Verlag Stuttgart · New York

A. M. van Berkel1 , D. L. Cahen1 , D. J. van Westerloo1 , E. A. J. Rauws1 , K. Huibregtse1 , M. J. Bruno1

Further Information

Publication History

Submitted 11 July 2003

Accepted after Revision 30 November 2003

Publication Date:
21 April 2004 (online)

Background and Study Aims: In selected patients with chronic pancreatitis in whom conventional plastic stenting fails and in whom surgery is contraindicated or declined, insertion of a biliary self-expanding metal stent (SEMS) may be a valuable treatment option.
Patients and Methods: Between 1994 and 1999, 13 patients with chronic pancreatitis received SEMS for benign biliary strictures (four women and nine men; mean age 56). The indications for SEMS placement were: contraindication to surgery (n = 10), presumed inoperable pancreatic carcinoma (n = 1), concomitant unresectable lung cancer (n = 1), and declined surgery (n = 1). The success of treatment was defined as adequate biliary drainage due to SEMS therapy.

Results: The mean follow-up period was 50 months (range 6 days - 86 months). Nine patients (69 %) were successfully treated with SEMS therapy: a patent first SEMS (n = 5); a patent second SEMS inserted through the first SEMS (n = 3); and one patent SEMS after balloon cleaning. SEMS treatment was not successful in four patients (due to stent migration in one case and occlusion in three ). The mean patency period of the SEMS was 60 months (95 % CI, 43 months - 77 months). At 33 months, the probability of adequate biliary drainage with SEMS therapy was 75 %.

Conclusions: SEMS therapy was safe and provided successful and prolonged biliary drainage in a selected group of patients with benign biliary strictures due to chronic pancreatitis in whom surgical intervention was not possible or desirable.

References

A. M. van Berkel, M. D.

Dept. of Gastroenterology and Hepatology C2 - 220 · Academic Medical Center

Meibergdreef 9 · 1105 AZ Amsterdam · The Netherlands

Fax: +31-20-6917033 ·

Email: a.m.vanberkel@amc.uva.nl