Drug Toxicity, HIV Progression, or Comorbidity of Aging: Does Tipranavir Use Increase the Risk of Intracranial Hemorrhage? (original) (raw)

Journal Article

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1

Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

2

Yale University

,

West Haven, Connecticut

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University of California–Los Angeles

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West Haven, Connecticut

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Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

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Yale University

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West Haven, Connecticut

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1

Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

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Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

2

Yale University

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West Haven, Connecticut

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Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

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Yale University

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West Haven, Connecticut

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Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

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Yale University

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West Haven, Connecticut

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Pfizer, New York City

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New York

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Boehringer Ingelheim

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Ingelheim, Germany

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Veterans Affairs Connecticut Healthcare System

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West Haven, Connecticut

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Yale University

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West Haven, Connecticut

Reprints or correspondence: Dr. Kristin M. Mattocks, VA Connecticut Healthcare System, 950 Campbell Ave., 11-ACSLG, West Haven, CT 06516 (kristin.mattocks@va.gov).

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Published:

01 November 2008

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Amy C. Justice, David S. Zingmond, Kirsha S. Gordon, Shawn L. Fultz, Joseph L. Goulet, Joseph T. King, Dawn M. Bravata, Hernan Valdez, Michael Kraft, Kristin M. Mattocks, the Veterans Aging Cohort Study Project Team, Drug Toxicity, HIV Progression, or Comorbidity of Aging: Does Tipranavir Use Increase the Risk of Intracranial Hemorrhage?, Clinical Infectious Diseases, Volume 47, Issue 9, 1 November 2008, Pages 1226–1230, https://doi.org/10.1086/592302
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Abstract

The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.

© 2008 by the Infectious Diseases Society of America

Topic:

• aging
• hiv
• intracranial hemorrhages
• comorbidity
• drug toxicity
• united states food and drug administration
• tipranavir

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