Completely Resistant Acinetobacter baumannii Strains | Infection Control & Hospital Epidemiology | Cambridge Core (original) (raw)

Abstract

Nosocomially acquired completely resistant Acinetobacter baumannii strains are a major clinical concern. We identified completely resistant A. baumannii in 6 (4.9%) of 122 A. baumannii isolates in a retrospective chart review at two teaching hospitals. All of these patients had received broad-spectrum antibiotics and had severe underlying comorbid illnesses, long hospitalizations, or recent surgical procedures; 3 had been in the intensive care unit. Five (83%) of the 6 patients were older than 70 years. Only one death occurred. Strict infection control measures may limit further spread.

References

1.Koeleman, JG, Parlevliet, GA, Dijkshoorn, L, et al. Nosocomial outbreak of multi-resistant Acinetobacter baumannii on a surgical ward: epidemiology and risk factors for acquisition. J Hosp Infect 1997;37:113–123.Google Scholar

2.Kaul, R, Burt, JA, Cork, L, et al. Investigation of a multiyear multiple critical care unit outbreak due to relatively drug-sensitive Acinetobacter baumannii. J Infect Dis 1996;174:1279–1287.CrossRef Google Scholar PubMed

3.Lortholary, O, Fagon, JY, Hoi, AB, et al. Nosocomial acquisition of multiresistant Acinetobacter baumannii: risk factors and prognosis. Clin Infect Dis 1995;20:790–796.CrossRef Google Scholar PubMed

4.Husni, RN, Goldstein, LS, Arroliga, AC, et al. Risk factors for an outbreak of multi-drug resistant Acinetobacter nosocomial pneumonia among intubated patients. Chest 1999;115:1378–1382.Google Scholar

5.Villers, D, Espaze, E, Coste-Burel, M, et al. Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology. Ann Intern Med 1998;129:182–189.Google Scholar

6.Manikal, VM, Landman, D, Saurina, G, Oydna, E, Lai, H, Quale, J. Endemic carbapenem-resistant Acinetobacter species in Brooklyn, New York: city-wide prevalence, interinstitutional spread, and relation to antibiotic usage. Clin Infect Dis 2000;31:101–106.Google Scholar

7.Baraibar, J, Correa, H, Mariscal, D, Gallego, M, Valles, J, Rello, J. Risk factors for infection by Acinetobacter baumannii in intubated patients with nosocomial pneumonia. Chest 1997;112:1050–1054.CrossRef Google Scholar PubMed

8.Mulin, B, Talon, D, Viel, JF, et al. Risk factors for nosocomial colonization with multiresistant Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis 1995;14:569–576.Google Scholar

9.Okpara, AU, Maswoswe, JJ. Emergence of multidrug-resistant isolates of Acinetobacter baumannii. American Journal of Hospital Pharmacy 1994; 51:2671–2675.Google Scholar

10.Garcia-Garmendia, JL, Ortiz-Leyba, C, Garnacho-Montero, J, et al. Mortality and the increased length of stay attributable to the acquisition of Acinetobacter in critically ill patients. Crit Care Med 1999;27:1794–1798.Google Scholar