Improvement in Prescribing Habits and Economic Outcomes Associated With the Introduction of a Standardized Approach for Surgical Antimicrobial Prophylaxis | Infection Control & Hospital Epidemiology | Cambridge Core (original) (raw)

Abstract

A quasi-experimental before-after study was conducted to determine the impact on prescribing habits and economic outcomes of an intervention that required use of an order form for surgical antimicrobial prophylaxis. Implementation of this intervention improved compliance with guidelines for prevention of surgical site infections, particularly with respect to choice of antibiotic, duration of use, and dosage, and resulted in decreased cost of surgical prophylaxis.

Type

Concise Communications

Copyright

Copyright © The Society for Healthcare Epidemiology of America 2008

References

2.Bratzier, DW, Houck, PM. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Am J Surg 2005;189:395–404.CrossRefGoogle Scholar

3.Antimicrobial prophylaxis in surgery. Med Lett Drugs Ther 2001;43:92–97.Google Scholar

4.Dellinger, EP, Gross, PA, Barrett, TL, et al.Quality standard for antimicrobial prophylaxis in surgical procedures. Infectious Diseases Society of America. Clin Infect Dis 1994;18:422–427.CrossRefGoogle ScholarPubMed

5.Gilbert, DN, Moellering, RC, Eliopoulos, GM, Sande, MA. The Sanford Guide to Antimicrobial Therapy. 37th ed. Hyde Park, VT; 2007.Google Scholar

6.Mangram, AJ, Horan, TC, Pearson, ML, Silver, LC, Jarvis, WR. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 1999;20:250–278; quiz 279-280.Google Scholar

7.Page, CP, Bohnen, JM, Fletcher, JR, McManus, AT, Solomkin, JS, Wittmann, DH. Antimicrobial prophylaxis for surgical wounds. Guidelines for clinical care. Arch Surg 1993;128:79–88.Google Scholar

8.American Society for Health-System Pharmacists. ASHP therapeutic guidelines on antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 1999;56:1839–1888.CrossRefGoogle Scholar

10.Classen, DC, Evans, RS, Pestotnik, SL, Horn, SD, Menlove, RL, Burke, JP. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Eng J Med 1992;326:281–286.CrossRefGoogle ScholarPubMed

11.Stone, HH, Hooper, CA, Kolb, LD, Geheber, CE, Dawkins, EJ. Antibiotic prophylaxis in gastric, biliary and colonic surgery. Ann Surg 1976;184:443–452.Google Scholar