GeneCards™ 2002: towards a complete, object-oriented, human gene compendium (original) (raw)

Marilyn Safran, Irina Solomon, Orit Shmueli, Michal Lapidot, Shai Shen-Orr, Avital Adato, Uri Ben-Dor, Nir Esterman, Naomi Rosen, Inga Peter, Tsviya Olender, Vered Chalifa-Caspi, Doron Lancet, GeneCards™ 2002: towards a complete, object-oriented, human gene compendium, Bioinformatics, Volume 18, Issue 11, November 2002, Pages 1542–1543, https://doi.org/10.1093/bioinformatics/18.11.1542
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Abstract

Motivation: In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools.

Results: GeneCards (Rebhan et al., 1998) has made innovative strides: (a) regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b) restructured software using object-oriented Perl, migration to schema-driven XML, and (c) pilot studies, introducing methods to produce cards for novel and predicted genes.

Availability: Freely available for educational and research purposes by non-profit institutions at http://bioinfo.weizmann.ac.il/cards and academic mirror sites. Commercial usage requires a license.

Contact: [email protected]

Supplementary Information: http://bioinfo.weizmann.ac.il/cards/9pageGC2002Bioinformatics.doc; http://bioinfo.weizmann.ac.il/cards/GeneCardByResource.xsd and http://bioinfo.weizmann.ac.il/cards/GeneCardByFunction.xsd.

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