AGenDA: homology-based gene prediction (original) (raw)
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Accepted:
14 February 2002
Revision received:
30 November 2002
Published:
12 August 2003
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Leila Taher, Oliver Rinner, Saurabh Garg, Alexander Sczyrba, Michael Brudno, Serafim Batzoglou, Burkhard Morgenstern, AGenDA: homology-based gene prediction, Bioinformatics, Volume 19, Issue 12, August 2003, Pages 1575–1577, https://doi.org/10.1093/bioinformatics/btg181
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Abstract
Summary: We present a www server for homology-based gene prediction. The user enters a pair of evolutionary related genomic sequences, for example from human and mouse. Our software system uses CHAOS and DIALIGN to calculate an alignment of the input sequences and then searches for conserved splicing signals and start/stop codons around regions of local sequence similarity. This way, candidate exons are identified that are used, in turn, to calculate optimal gene models. The server returns the constructed gene model by email, together with a graphical representation of the underlying genomic alignment.
Availability: http://bibiserv.TechFak.Uni-Bielefeld.DE/agenda/
Contact: ltaher@TechFak.Uni-Bielefeld.DE
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© Oxford University Press 2003
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