GOLDsurfer: three dimensional display of linkage disequilibrium (original) (raw)

Abstract

Summary: GOLDsurfer is a java-based analysis and graphics program for three-dimensional plotting of linkage disequilibrium (LD). Simultaneous presentation of LD measures, including recombination rate estimates and disease association statistics, helps to clarify LD patterns and facilitates interpretations based on multiple indices of local genetic data.

Availability: GOLDsurfer is available at www.umbio.com and is embedded with the Evince graphical software package.

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Author notes

1Department of Organic Chemistry, Umeä University, Sweden, 2Umbio AB, Umeä, Sweden and 3Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK