Flat Adenomas in a Colon Cancer-Prone Kindred12 (original) (raw)
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3
Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
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Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
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3
Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
Search for other works by this author on:
,
3
Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
Search for other works by this author on:
,
3
Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
Search for other works by this author on:
,
3
Departments of Preventive Medicine/Public Health (H. T. Lynch, M. Kriegler. J. F. Lynch), Pathology (T. Smyrk, J. N. Marcus), Medicine Gastroenterology (S. J. Lanspa), Creighton University School of Medicine, and the Hereditary Cancer Consultation Center
Califonia at 24thst, Omaha, NE 68178.
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4
Department of Pathology, University of Michigan Medical School
Ann Arbort, MI.
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Revision received:
02 February 1988
Accepted:
04 February 1988
Received:
22 December 1988
Cite
Henry T. Lynch, Tom Smyrk, Stephen J. Lanspa, Joseph N. Marcus, Mary Kriegler, Jane F. Lynch, Henry D. Appelman, Flat Adenomas in a Colon Cancer-Prone Kindred1, JNCI: Journal of the National Cancer Institute, Volume 80, Issue 4, 20 April 1988, Pages 278–282, https://doi.org/10.1093/jnci/80.4.278
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Abstract
We describe new pathologic findings in a hereditary nonpolyposis colorectal cancer family. Affected family members developed multiple small adenomas with right-sided predominance; many adenomas had an unusual appearance featuring slightly elevated lesions with adenomatous changes confined to the upper regions of the colonic crypts. We have adopted the previously established term “flat adenoma” for these lesions. This phenotype may be a morphologic marker for at least one subset of hereditary nonpolyposis colorectal cancer. [J Natl Cancer Inst 1988;80:278–282]
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