Capping structures of simian virus 40 19S and 16S mRNAs (original) (raw)
Journal Article
,
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Departments of Virology, The Weizmann Institute of Science
Rehovot, Israel
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,
*
Departments of Virology, The Weizmann Institute of Science
Rehovot, Israel
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**
Departments of Genetics, The Weizmann Institute of Science
Rehovot, Israel
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Received:
02 September 1977
Published:
01 November 1977
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Abstract
In vivo [methyl 3 H]-labeled SV40 19S and 16S mRNA species were purified and their internal methylation as well as their capping structures analyzed. SV40 viral mRNA sedimenting in the 19S region contains approximately equal proportions of m 7 GpppAm and m 7 Gpppm 6 Am, while the 16S mRNA contains mainly m 7 Gpppm 6 Am. N 6 methyl adenosine is located internally within the RNA chains of both the 19S and 16S species.
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