A comprehensive sequence analysis program for the IBM personal computer (original) (raw)

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Laboratory of Biochemistry, National Cancer Institute

Bethesda, MD 20205

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Department of Genetics, School of Medicine, Stanford University

Stanford, CA 94305, USA

*Correspondence and requests for reprints should be addressed to Dr. Laurence Jay Korn. The program described here and compatible copies of the National Sequence Data Bank are available from SciSoft Inc., No. 189, 1259 El Camino Real, Menlo Park, California 94025.

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*Correspondence and requests for reprints should be addressed to Dr. Laurence Jay Korn. The program described here and compatible copies of the National Sequence Data Bank are available from SciSoft Inc., No. 189, 1259 El Camino Real, Menlo Park, California 94025.

Author Notes

Published:

11 January 1984

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Abstract

We have developed a versatile program for the analysis of nucleic acid and protein sequences on the IBM Personal Computer. The program is interactive and self-instructing. Tt contains all the features generally found in sequence analysis programs on large computers, including extensive homology routines, as well as new procedures for the entry of sequence data. The program contains facilities to store and utilize the entire Nucleic Acid Sequence Data Bank. We have devised a new algorithm to find restriction enzyme sites, which allows our microcomputer program to find all sites on a small plasmid for 100 different enzymes in 1 to 2 minutes.

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Author notes

*Correspondence and requests for reprints should be addressed to Dr. Laurence Jay Korn. The program described here and compatible copies of the National Sequence Data Bank are available from SciSoft Inc., No. 189, 1259 El Camino Real, Menlo Park, California 94025.

© 1984 IRL Press Limited

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