Statistical analysis of mammalian pre-mRNA splicing sites (original) (raw)
Journal Article
Institute of Protein Research, USSR Academy of Sciences
Puschino, Moscow region 142292, USSR
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Received:
04 February 1989
Revision received:
22 June 1989
Published:
11 August 1989
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Abstract
222 donor and 222 acceptor (including 206 pairs) non-homologous splicing sites were studied. Well known features of these were confirmed and some novel observations were made. It is (1) cCAGGGag signal in (−60)–(−58) region of acceptor sites; (2) strong complementarity between regions (−69)–(−55) and (−36)–(−22) of some of the acceptor sites, and (3) small but statistically significant correlation between discrimination energies of corresponding donor and acceptor sites.
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