Language-related brain function during word repetition in... : NeuroReport (original) (raw)
BRAIN IMAGING
Language-related brain function during word repetition in post-stroke aphasics
Abo, MasahiroCA; Senoo, Atushi1; Watanabe, Shu1; Miyano, Satoshi; Doseki, Keiko; Sasaki, Nobuyuki; Kobayashi, Kazushige2; Kikuchi, Yoshiaki1; Yonemoto, Kyozo1
Departments of Rehabilitation Medicine, Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo 105-8461
1 Tokyo Metropolitan University of Health Science, 7-2-10, Higashi-Ogu, Arakawa-ku, Tokyo 116-8551
2 Tokyo Women's Medical College, 8-1, Kawadachou, Shinjuku-ku, Tokyo 162-8666, Japan
CACorresponding Author: [email protected]
Received 23 June 2004; accepted 25 June 2004
Abstract
We compared fMRI findings (using SPM99) obtained with repetition task in normal subjects with those of two patients with Broca's and Wernicke's aphasia who received speech therapy and showed complete recovery. Both aphasic patients with left hemisphere damage who showed complete recovery exhibited activation of only the compensatory area in the right hemisphere during the repetition task. Recovery from Broca's aphasia involves reorganization and neuromodulation between the external temporopolar area and the anterior superior temporal area of the superior temporal gyrus, putamen and the inferior frontal gyrus, while that from Wernicke's aphasia involves reorganization and neuromodulation between the superior temporal gyrus of the temporal region, the posterior supramarginal gyrus and inferior parietal lobule of the parietal region.
© 2004 Lippincott Williams & Wilkins, Inc.