Association of a Dietary Inflammatory Index With... : Journal of Occupational and Environmental Medicine (original) (raw)

Original Articles

Association of a Dietary Inflammatory Index With Inflammatory Indices and Metabolic Syndrome Among Police Officers

Wirth, Michael D. MSPH, PhD; Burch, James MS, PhD; Shivappa, Nitin MBBS, MPH; Violanti, John M. PhD; Burchfiel, Cecil M. PhD, MPH; Fekedulegn, Desta PhD; Andrew, Michael E. PhD; Hartley, Tara A. PhD, MPA, MPH; Miller, Diane B. PhD; Mnatsakanova, Anna MS; Charles, Luenda E. PhD, MPH; Steck, Susan E. PhD, MPH, RD; Hurley, Thomas G. MSc; Vena, John E. PhD; Hébert, James R. ScD

From the Cancer Prevention and Control Program (Dr Wirth, Dr Burch, Dr Shivappa, Dr Steck, Mr Hurley, and Dr Hébert) and Department of Epidemiology and Biostatistics (Drs Burch, Shivappa, Steck, and Hébert), University of South Carolina, Columbia; WJB Dorn VA Medical Center (Dr Burch), Columbia, SC; Department of Social and Preventive Medicine (Dr Violanti), School of Public Health and Health Professions, University of Buffalo, The State University of New York; Biostatistics and Epidemiology Branch (Dr Burchfiel, Dr Fekedulegn, Dr Andrew, Dr Hartley, Ms Mnatsakanova, and Dr Charles) and Toxicology and Molecular Biology Branch (Dr Miller), Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, WV; and Department of Epidemiology and Biostatistics (Dr Vena), College of Public Health, University of Georgia, Athens, and Department of Public Health Sciences, Medical University of South Carolina, Charleston.

Address correspondence to: Michael Wirth, MSPH, PhD, Cancer Prevention and Control Program, University of South Carolina, 915 Greene St, Suite 200, Columbia, SC 29208 ([email protected]).

This work was supported by the National Institute for Occupational Safety and Health contract number 200-2003-01580. Dr Wirth's participation was supported through an ASPIRE-II Grant from the University of South Carolina Office of Research and by the South Carolina Cancer Prevention and Control Research Network funded under Cooperative Agreement Number 3U48DP001936-01 from the Centers for Disease Control and Prevention and the National Cancer Institute. Dr. Hébert is supported by an Established Investigator Award in Cancer Prevention and Control from the Cancer Training Branch of the National Cancer Institute (K05 CA136975). The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, or the National Cancer Institute.

The authors declare no conflicts of interest.

Abstract

Objectives:

To determine whether the dietary inflammatory index (DII) is associated with inflammatory or metabolic biomarkers and metabolic syndrome (MetSyn) among police officers.

Methods:

Cross-sectional data from the Buffalo Cardio-Metabolic Occupational Police Stress study were derived from saliva and fasting blood samples, anthropometric measurements, long-term shiftwork histories, and demographic, stress/depression, and food frequency questionnaires (FFQs). Metabolic syndrome was defined using standard criteria.

Results:

Officers in DII quartiles 2 to 4 were more likely to exceed a threshold of 3.0 mg/L for C-reactive protein (odds ratio [OR] = 1.88; 95% confidence interval [95% CI] = 1.02 to 3.45; OR = 2.17; 95% CI = 1.19 to 3.95; OR = 1.57; 95% CI = 0.85 to 2.88, respectively) compared with quartile 1. The glucose intolerance component of MetSyn was more prevalent among officers in DII quartile 4 than among those in quartile 1 (OR = 2.03; 95% CI = 1.08 to 3.82).

Conclusions:

A pro-inflammatory diet was associated with elevated CRP and with the glucose intolerance component of MetSyn.