Triglyceride synthesis: insights from the cloning... : Current Opinion in Lipidology (original) (raw)

Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase

Robert V. Farese
Sylvaine Cases
Steven J. Smith

Current Opinion in Lipidology

11(3):p 229-234, June 2000.

Although the biochemistry of triglyceride synthesis has been studied for decades, an understanding of the molecular processes involved has been lacking. The recent cloning of a gene encoding acyl coenzyme A : diacylglycerol acyltransferase, an enzyme that catalyses the final step in triglyceride synthesis, has opened this area to molecular investigation and has begun to provide new insights into triglyceride metabolism.