The leukocyte β1 integrins : Current Opinion in Hematology (original) (raw)
Articles: PDF Only
Dana-Farber Cancer Institute, Boston, and Biogen, Cambridge, Massachusetts, USA
Abstract
We summarize publications appearing in the past year on the blood cell β1 integrins VLA-1 through -6, including characterization of their ligand interactions, activation epitopes, signaling mechanisms, cellular distribution, and in vivo relevance. These studies extend our understanding of the β1 integrins, and continue to underscore their importance in leukocyte biology, which derives from their central role in mechanisms of cellular adhesion, growth, and differentiation.
© Lippincott-Raven Publishers.