Anticellular Effects of 9-(2-Hydroxyethoxymethyl) Guanine Against Herpes Simplex Virus-transformed Cells (original) (raw)

Abstract

SUMMARY

The guanine derivative 9-(2-hydroxyethoxymethyl) guanine (acycloguanosine), a potent inhibitor of herpes simplex virus (HSV) multiplication, was found to have marked anticellular activity against HSV-transformed thymidine kinase-positive cells. HSV type 1-transformed cells were more sensitive to the drug than HSV type 2-transformed cells.

• Received: 26/01/1979
• Accepted:30/05/1979
• Published Online:01/10/1979

© Journal of General Virology 1979

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/content/journal/jgv/10.1099/0022-1317-45-1-227

1979-10-01

2025-02-14

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