Characterization of Herpes Simplex Virus Strains Differing in their Effects on Social Behaviour of Infected Cells (original) (raw)

Abstract

Summary

Established (laboratory) strains and fresh isolates of herpes simplex virus from patients with skin and genital lesions were classified into four groups depending on their effects on the social interaction among infected hep-2 cells. The groups comprised strains causing (1) rounding of cells but no adhesion or fusion, (2) loose aggregation of rounded cells, (3) tight adhesion of rounded cells, and (4) fusion of cells into polykaryocytes. Protype strains from each group were found to differ with respect to immunologic specificity, buoyant density in CsCl solutions and stability at 4°.

• Received: 06/09/1967
• Accepted:13/11/1967
• Published Online:01/05/1968

© Society for General Microbiology 1968

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/content/journal/jgv/10.1099/0022-1317-2-3-357

1968-05-01

2024-10-17

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