Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA (original) (raw)

Abstract

SUMMARY

Vero cells infected with herpes simplex virus in the presence of actinomycin or cycloheximide, or with u.v.-inactivated virus, suffered a rapid loss of functional mRNA as determined by translation in vitro. It is suggested that a virion-associated factor causes a structural change in the mRNA of the host cell.

Received: 19/01/1984
Accepted:05/04/1984
Published Online:01/07/1984

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-65-7-1225

1984-07-01

2024-10-22

Full text loading...

/deliver/fulltext/jgv/65/7/JV0650071225.html?itemId=/content/journal/jgv/10.1099/0022-1317-65-7-1225&mimeType=html&fmt=ahah