Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines (original) (raw)

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Abstract

The complete nucleotide sequences of the human papillomavirus type 16 (HPV-16) variants present in the CaSki and SiHa cervical carcinoma cell lines and the primary subgenomic HPV-18 variant present in the HeLa cervical carcinoma cell line were determined using overlapping bulk PCR products as templates. PCR-based methods were also used to characterize five previously unreported CaSki HPV-16 genomic disruptions and the 5′ cellular-viral junction common to all HeLa HPV-18 subgenomic structures.

• Received: 25/11/1998
• Accepted:25/02/1999
• Published Online:01/07/1999

© Journal of General Virology 1999

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1999-07-01

2025-01-23

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