Adhesion of human Lactobacillus acidophilus strain LB to human enterocyte-like Caco-2 cells (original) (raw)

• _info_Info
  • Article information
  • Full-Text
  • Figures and Tables
  • References (37)
  • Cited By (197)
  • Supplementary Material
  • Metrics
• _list_Sections

Abstract

Twenty-five strains of lactobacilli were tested for their ability to adhere to human enterocyte-like Caco-2 cells in culture. Seven Lactobacillus strains adhered well to the Caco-2 cells, of which three possessed calcium-independent adhesion properties. A high level of calcium-independent adhesion was observed with the human stool isolate Lactobacillus acidophilus strain LB. Scanning electron microscopy revealed that this strain adhered to the apical brush border of the cells. Adhesion increased in parallel with the morphological and functional differentiation of the Caco-2 cells. Two Lactobacillus components were involved in this adhesion. One was protease-resistant and bacterial-surface-associated; the other was heat-stable, extracellular and protease-sensitive.

• Received: 29/11/1991
• Accepted:13/05/1992
• Revised:13/04/1992
• Published Online:01/08/1992

© Society for General Microbiology, 1992

Article metrics loading...

/content/journal/micro/10.1099/00221287-138-8-1689

1992-08-01

2024-11-18

Full text loading...

/deliver/fulltext/micro/138/8/mic-138-8-1689.html?itemId=/content/journal/micro/10.1099/00221287-138-8-1689&mimeType=html&fmt=ahah

Most read this month

Article

content/journal/micro

Journal

5

3

false

en