Loss of ciliary activity in organ cultures of rat trachea treated with lipo-oligosaccharide from Haemophilus influenzae (original) (raw)

Abstract

Summary

Organ culture of rat trachea was used as an experimental model to examine the ability of lipo-oligosaccharide from Haemophilus influenzae to damage respiratory tract mucosal tissue. Lipo-oligosaccharide from two strains of H. influenzae produced a significant decrease in the ciliary activity of tracheal rings observed over a 3-5 day period. No loss of ciliary activity was observed with the lipid-free moiety of the lipooligosaccharide.

Received: 12/03/1986
Accepted:19/03/1986
Published Online:01/11/1986

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/content/journal/jmm/10.1099/00222615-22-3-265

1986-11-01

2025-01-18

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