MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems (original) (raw)

1. Stephen M. Cohen1,2,3
2. 1Institute of Molecular and Cell Biology, Singapore 138673;
3. 2Department of Biological Sciences, National University of Singapore, Singapore 117604

Abstract

Biological systems are continuously challenged by an environment that is variable. Yet, a key feature of developmental and physiological processes is their remarkable stability. This review considers how microRNAs contribute to gene regulatory networks that confer robustness.

• MicroRNAs
• noise
• robustness
• regulatory networks

Footnotes

• ↵3 Corresponding author.
  E-MAIL scohen{at}imcb.a-star.edu.sg; FAX 65-6872-7089.

• Article is online at http://www.genesdev.org/cgi/doi/10.1101/gad.1937010.

• Copyright © 2010 by Cold Spring Harbor Laboratory Press

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