Liquid-Liquid Phase Separation in Biology (original) (raw)

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Abstract

Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.

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/content/journals/10.1146/annurev-cellbio-100913-013325

2014-10-06

2024-10-21

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