Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31→q32.1 (original) (raw)

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2000

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Cytogenetics and Cell Genetics

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Research Articles| October 06 2000

M.Z. Limongi;

Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Roma (Italia)

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F. Pelliccia;

Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Roma (Italia)

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L. Gaddini;

Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Roma (Italia)

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A. Rocchi

Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Roma (Italia)

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Cytogenetics and Cell Genetics (2000) 90 (1-2): 151–153.

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Abstract

In this study we have used FISH to examine the relationship between a group of homeobox genes, namely DLX1/DLX2, EVX2 and four HOXD genes (10, 11, 12, 13), that map to region q31 on chromosome 2, and the FRA2G and FRA2H fragile sites located at 2q31 and 2q32.1 respectively. Our results indicate that these homeobox genes lie between the two fragile regions.

References

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© 2000 S. Karger AG, Basel

2000

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