Nutritional Support in Acute Pancreatitis (original) (raw)

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Review Articles| October 29 2003

Costas Avgerinos;

1st Department of Surgery, Konstantopoulion, Agia Olga Hospital, Athens, Greece

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Spiros Delis;

1st Department of Surgery, Konstantopoulion, Agia Olga Hospital, Athens, Greece

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Spyros Rizos;

1st Department of Surgery, Konstantopoulion, Agia Olga Hospital, Athens, Greece

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Christos Dervenis

1st Department of Surgery, Konstantopoulion, Agia Olga Hospital, Athens, Greece

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Dig Dis (2003) 21 (3): 214–219.

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Abstract

Acute pancreatitis (AP), mainly the severe necrotizing type, results in extreme energy demands which might lead, if prolonged, to severe malnutrition. Besides that, starving during AP contributes to gut barrier dysfunction, the main cause of bacterial translocation and sepsis. The aim of nutritional support in AP is to prevent malnutrition and protect the gut by maintaining mucosal integrity. Traditionally, nutritional support during the acute phase of the disease has been provided through total parenteral nutrition (TPN) solutions. However, recent animal and human studies have identified new patterns of pancreatic secretion and hormonal stimulation during the course of AP, different from those assumed for years. Thus it has become feasible to use the natural enteral route for nutrition with potential benefits compared with TPN.

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© 2003 S. Karger AG, Basel

2003

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