Neoplastic Characteristics of the DNA Found in the Plasma of Cancer Patients (original) (raw)

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Research Articles| June 26 2009

M. Stroun;

aDépartement de Physiologie végétale, Faculté des Sciences, Université de Genève, Suisse;

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P. Anker;

aDépartement de Physiologie végétale, Faculté des Sciences, Université de Genève, Suisse;

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P. Maurice;

bDivision d’Onco-Hématologie, Département de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse;

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J. Lyautey;

bDivision d’Onco-Hématologie, Département de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse;

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C. Lederrey;

aDépartement de Physiologie végétale, Faculté des Sciences, Université de Genève, Suisse;

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M. Beljanski

cLaboratoire de Pharmacodynamic, Faculté des Sciences pharmaceutiques, Châtenay-Malabry, France.

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Oncology (1989) 46 (5): 318–322.

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Abstract

About one third of patients with various malignant diseases were found to have extractable amounts of DNA in their plasma whereas no DNA could be detected in normal controls. Using the test established by one of us (M. B.), which is based on decreased strand stability of cancer cell DNA, we have found that several plasma DNA originate from cancer cells.

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© 1989 S. Karger AG, Basel

1989

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