Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome (original) (raw)

Information & Authors

Information

Published In

American Journal of Psychiatry

History

Received: 5 July 2013

Revision received: 4 November 2013

Accepted: 19 December 2013

Published online: 1 June 2014

Published in print: June 2014

Authors

Details

Maude Schneider, M.Sc.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Martin Debbané, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Anne S. Bassett, M.D., F.R.C.P.C.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Eva W.C. Chow, M.D., F.R.C.P.C.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Wai Lun Alan Fung, M.D., Sc.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Marianne B.M. van den Bree, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Michael Owen, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Kieran C. Murphy, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Maria Niarchou, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Wendy R. Kates, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Kevin M. Antshel, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Wanda Fremont, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Donna M. McDonald-McGinn, M.S., C.G.C.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Raquel E. Gur, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Elaine H. Zackai, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Jacob Vorstman, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Sasja N. Duijff, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Petra W.J. Klaassen, M.Sc.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Ann Swillen, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Doron Gothelf, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Tamar Green, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Abraham Weizman, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Therese Van Amelsvoort, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Laurens Evers, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Erik Boot, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Vandana Shashi, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Stephen R. Hooper, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Carrie E. Bearden, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Maria Jalbrzikowski, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Marco Armando, M.D., Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Stefano Vicari, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Declan G. Murphy, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Opal Ousley, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Linda E. Campbell, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Tony J. Simon, Ph.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Stephan Eliez, M.D.

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

for the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

From the Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva; the Clinical Genetics Research Program and Clinical Genetics Service, Centre for Addiction and Mental Health, Toronto; the Dalglish Family Hearts and Minds Clinic for 22q11.2 Deletion Syndrome, University Health Network, Toronto; the Department of Psychiatry, University of Toronto; the Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, U.K.; the Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin; the Department of Psychiatry and Behavioral Sciences, State University of New York at Upstate Medical University, Syracuse, N.Y.; the Department of Psychology, Syracuse University, Syracuse, N.Y.; the Division of Human Genetics, Children’s Hospital of Philadelphia; the Departments of Pediatrics and Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center, Utrecht, the Netherlands; the Department of Pediatric Psychology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, the Netherlands; the Centre for Human Genetics, University Hospital Gasthuisberg, and the Department of Human Genetics, University of Leuven, Leuven, Belgium; the Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif.; the Geha Mental Health Center and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Petah Tiqwa, Israel; the Department of Psychiatry and Psychology, Maastricht University, Maastricht, the Netherlands; the Koraalgroup, Heel, the Netherlands; Ipse de Bruggen, Centre for People with Intellectual Disability, Zwammerdam, the Netherlands; the Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, N.C.; the Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, N.C.; the Semel Institute for Neuroscience and Human Behavior and the Department of Psychology, University of California, Los Angeles; the Child Neuropsychiatry Unit, Department of Neuroscience, Bambino Gesù Children’s Hospital, Rome; the Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, King's College London; the Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta; the School of Psychology, University of Newcastle, Newcastle, Australia; the MIND Institute and Department of Psychiatry, University of California, Davis.

Notes

Funding Information

Dr. Ousley is a collaborator in a Biomarin Pharmaceutical study. The other authors report no financial relationships with commercial interests.

Supplementary Material

Supported by funding from the NIMH International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome; the Swiss National Fund to Dr. Eliez (grants PP00B_102864 and 32473B_121996); from the National Center of Competence in Research program Synapsy, financed by the Swiss National Science Foundation, to Dr. Eliez (grant 51AU40_125759); from the Canadian Institutes of Health Research to Drs. Bassett and Chow (grants MOP-97800, MOP-89066, and MOP-74631); from the Ontario Mental Health Foundation to Dr. Chow; from support of Dr. Bassett as the Canada Research Chair in Schizophrenia Genetics and Genomic Disorders and as the Dalglish Chair in 22q11.2 Deletion Syndrome; from the Baily Thomas Charitable Trust to Drs. van den Bree and Owen (grant 2315/1); from the Waterloo Foundation to Drs. van den Bree and Owen (grant 912-1234); from the Wellcome Trust Institutional Strategic Support Fund to Drs. van den Bree and Owen; from the Wellcome Trust to Dr. K.C. Murphy and Dr. Owen (grant GR067869MF); from Ireland’s Health Research Board to Dr. K.C. Murphy (grants RP/2004/30 and RP/2008/169); from the Health Foundation to Drs. K.C. Murphy and D.G. Murphy (grant 1206/188); from NIMH to Dr. Kates (grant MH-064824), Dr. Gur (grant MH-087626), Drs. McDonald-McGinn and Zackai (grant MH-087636), Dr. Shashi (grants MH-78015 and MH-091314), and Dr. Bearden (grant RO1 MH-085953); from the National Institute of Child Health and Human Development to Drs. McDonald-McGinn and Zackai (grant HD-070454), Dr. Bearden (P50 HD-055784 [CART pilot project grant]), and Dr. Simon (grant R01 HD-042974); from the Brain and Behavior Research Foundation (formerly NARSAD) to Dr. Vorstman (Young Investigator Award), Dr. Van Amelsvoort (Young Investigator Award), Dr. Armando (Young Investigator Award), and Dr. Ousley; from the State University of New York Hendricks Fund to Dr. Antshel; from the Basil O’Connor Starter Scholar Research Award by the March of Dimes to Dr. Gothelf (grant 5-FY06-590); from the Binational Science Foundation to Dr. Gothelf (grant 2011378); from the Gazit-Globe Award to Dr. Green; from the Dutch Brain Foundation to Dr. Van Amelsvoort; from the Robert W. Woodruff Fund to Dr. Ousley; from the Simons Foundation to Dr. Ousley; from a Hunter Medical Research Institute Post-Doctoral Fellowship to Dr. Campbell; and from an Australian Training Fellowship awarded by the National Health and Medical Research Council of Australia to Dr. Simon (grant 455614).