Clinical Hepatic Impairment after the Duodenal Switch (original) (raw)

Background: Nonalcoholic steatohepatitis (NASH) is the most common histological finding in morbidly obese patients undergoing liver biopsy. Biliopancreatic diversion has been widely used for the treatment of morbid obesity and hepatic steatosis, and very few cases of liver impairment as a complication of this operation have been reported. Methods: During the last 9 years, 470 morbidly obese patients were operated by means of a biliopancreatic diversion with duodenal switch ( BPD-DS), and 93 of them were performed laparoscopically. Results: 10 cases of clinical hepatic impairment occurred after the BPD-DS. The clinical course of these patients ranged from transient subclinical alterations of liver function tests to severe cases of jaundice and one death from liver failure. Conclusion: Randomized prospective studies with standardization of BPD-DS are needed, to know the real incidence of hepatic impairment and the proper treatment for this condition. Careful follow-up and correction of possible malnutrition should be addressed to avoid hepatic impairment and/or progression of liver disease.

Access this article

Log in via an institution

Subscribe and save

• Starting from 10 chapters or articles per month
• Access and download chapters and articles from more than 300k books and 2,500 journals
• Cancel anytime View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Author information

Authors and Affiliations

1. General Surgical Service, "Virgen de los Lirios" Hospital, Alcoy, Alicante, Spain
   Aniceto Baltasar MD
2. General Surgical Service, "Virgen de los Lirios" Hospital, Alcoy, Alicante, Spain
   Carlos Serra MD, PhD
3. General Surgical Service, "Virgen de los Lirios" Hospital, Alcoy, Alicante, Spain
   Nieves Pérez MD
4. General Surgical Service, "Virgen de los Lirios" Hospital, Alcoy, Alicante, Spain
   Rafael Bou MD
5. General Surgical Service, "Virgen de los Lirios" Hospital, Alcoy, Alicante, Spain
   Marcelo Bengochea MD

Authors

1. Aniceto Baltasar MD
2. Carlos Serra MD, PhD
3. Nieves Pérez MD
4. Rafael Bou MD
5. Marcelo Bengochea MD

Rights and permissions

About this article

Cite this article

Baltasar, A., Serra, C., Pérez, N. et al. Clinical Hepatic Impairment after the Duodenal Switch.OBES SURG 14, 77–83 (2004). https://doi.org/10.1381/096089204772787338

Download citation

• Published: 01 January 2004
• Issue date: January 2004
• DOI: https://doi.org/10.1381/096089204772787338