Manipulating Mouse Embryonic Stem Cells (original) (raw)
Abstract
In recent years, gene targeting technology has been rapidly evolving and has been used by a number of laboratories to systematically alter the mouse genome and to generate mice with specific targeted gene mutations. The improvement in the quality of reagents (embryonic stem (ES) cells and media) available to the scientific community has made this technology accessible to many laboratories.
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Authors and Affiliations
- Neural Development Group, Mouse Cancer Genetics, Program, NCI-Frederick Cancer Research and Development Center, Frederick, MD
Lino Tessarollo
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- Lino Tessarollo
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Editors and Affiliations
- National Vision Research Institute of Australia, Carlton, Victoria, Australia
Martin J. Tymms - Centre for Functional Genomics and Human Disease, Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia
Ismail Kola
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© 2001 Humana Press Inc., Totowa, NJ
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Tessarollo, L. (2001). Manipulating Mouse Embryonic Stem Cells. In: Tymms, M.J., Kola, I. (eds) Gene Knockout Protocols. Methods in Molecular Biology, vol 158. Humana Press. https://doi.org/10.1385/1-59259-220-1:47
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- DOI: https://doi.org/10.1385/1-59259-220-1:47
- Publisher Name: Humana Press
- Print ISBN: 978-0-89603-572-0
- Online ISBN: 978-1-59259-220-3
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