Differentiation of Mouse Thymocytes in Fetal Thymus Organ Culture (original) (raw)
References
Miller, J. F. A. P. (1961) Immunological function of the thymus. Lancet, 748–749. Google Scholar
Owen, J. J. T. and Ritter, M. A. (1969) Tissue interaction in the development of thymus lymphocytes. J. Exp. Med.129, 431–442. ArticlePubMedCAS Google Scholar
Owen, J. J. T. (1974) Ontogeny of the immune system. Prog. in Immunol.2, 163–173. Google Scholar
Mandel, T. and Russel, P. J. (1971) Differentiation of foetal mouse thymus. ultrastructure of organ cultures and of subcapsular grafts. Immunology21, 659–674. PubMedCAS Google Scholar
Mandel, T. E. and Kennedy, M. M. (1978) The differentiation of murine thymocytes in vivo and in vitro. Immunology35, 317–331. PubMedCAS Google Scholar
Jenkinson, E. J., van Ewijk, W., and Owen, J. J. T. (1981) Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice. J. Exp. Med.153, 280–292. ArticlePubMedCAS Google Scholar
Jenkinson, E. J., Franchi, L. L., Kingston, R., and Owen, J. J. T. (1982) Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: application in the production of chimeric thymus rudiments. Eur. J. Immunol.12, 583–587. ArticlePubMedCAS Google Scholar
Kingston, R., Jenkinson, E. J., and Owen, J. J. T. (1985) A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations. Nature317, 811–813. ArticlePubMedCAS Google Scholar
Anderson, G., Jenkinson, E. J., Moore, N. C., and Owen, J. J. T. (1993) MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus. Nature362, 70–73. ArticlePubMedCAS Google Scholar
Kisielow, P., Leiserson, W., and von Boehmer, H. (1984) Differentiation of thymocytes in fetal organ culture: analysis of phenotypic changes accompanying the appearance of cytolytic and interleukin-2-producing cells. J. Immunol.133, 1117–1123. PubMedCAS Google Scholar
Ceredig, R. (1988) Differentiation potential of 14-day fetal mouse thymocytes in organ culture. Analysis of CD4-CD8-defined single-positive and double-negative cells. J. Immunol.141, 355–362. PubMedCAS Google Scholar
Husmann, L. A., Shimonkevitz, R. P., Crispe, I. N., and Bevan, M. J. (1988) Thymocyte subpopulations during early fetal development in the BALB/c mouse. J. Immunol.141, 736–740. PubMedCAS Google Scholar
Takahama, Y., Hasegawa, T., Itohara, S., Ball, E. L., Sheard, M. A., and Hashimoto, Y. (1994) Entry of CD4−CD8− immature thymocytes into the CD4/CD8 developmental pathway is controlled by tyrosine kinase signals that can be provided through T cell receptor components. Int. Immunol.6, 1505–1514. ArticlePubMedCAS Google Scholar
Crompton, T., Gilmour, K. C., and Owen, M. J. (1996) The MAP kinase pathway controls differentiation from double-negative to double positive thymocyte. Cell86, 243–251. ArticlePubMedCAS Google Scholar
Heemskerk, M. H. M., Blom, B., Nolan, G., Stegmann, A. P. A., Bakker, A. Q., Weijer, K., Res, P. C. M., and Spits, H. (1997) Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J. Exp. Med.186, 1597–1602. ArticlePubMedCAS Google Scholar
Spain, L. M., Law, L. L., and Takahama, Y. (1998) Retroviral infection of T cell precursors in thymic organ culture, in Developmental Biology Protocols (Tuan, R. S. and Lo, C. W., eds.), Humana Press, Totowa, NJ, in press. Google Scholar
Sugawara, T., Di Bartolo, V., Miyazaki, T., Nakauchi, H., Acuto, O., and Takahama, Y. (1998) An improved retroviral transfer technique demonstrates inhibition of CD4−CD8− thymocyte development by kinase-inactive ZAP-70. J. Immunol.161, 2888–2894. PubMedCAS Google Scholar
Ikuta, K., Kina, T., MacNeil, I., Uchida, N., Peault, B., Chien, Y. H., and Weissman, I. L. (1990) A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell62, 863–874. ArticlePubMedCAS Google Scholar
Tsuda, S., Rieke, S., Hashimoto, Y., Nakauchi, H., and Takahama, Y. (1996) IL-7 supports D-J but not V-DJ rearrangement of T cell receptor β gene in fetal liver progenitor cells. J. Immunol.156, 3233–3242. PubMedCAS Google Scholar
Sagara, S., Sugaya, K., Tokoro, Y., Tanaka, S., Takano, H., Kodama, H., Nakauchi, H., and Takahama, Y. (1997) B220 expression by T lymphoid progenitor cells in mouse fetal liver. J. Immunol.158, 666–676. PubMedCAS Google Scholar
Theiler, K. (1989) The House Mouse. Springer-Verlag, New York, NY. Google Scholar
Kaufman, M. H. (1992) The Atlas of Mouse Development. Academic, San Diego, CA. Google Scholar
Butler, H. and Juurlink, B. H. (1987) An Atlas for Staging Mammalian and Chick Embryos. CRC, Boca Raton, FL. Google Scholar
Takahama, Y., Suzuki, H., Katz, K. S., Grusby, M. J., and Singer, A. (1994) Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC. Nature371, 67–70. ArticlePubMedCAS Google Scholar
Takahama, Y. and Nakauchi, H. (1996) Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells. J. Immunol.157, 1508–1513. PubMedCAS Google Scholar
Tokoro, Y., Tsuda, S., Tanaka, S., Nakauchi, H., and Takahama, Y. (1996) CD3-induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T-cell antigen receptor. Eur. J. Immunol.26, 1012–1017. ArticlePubMedCAS Google Scholar
Watanabe, Y. and Katsura, Y. (1993) Development of T cell receptor αβ-bearing T cells in the submersion organ culture of murine fetal thymus at high oxygen concentration. Eur. J. Immunol.23, 200–205. ArticlePubMedCAS Google Scholar