Association of Accelerometer-Measured Sedentary Behavior... : Official journal of the American College of Gastroenterology | ACG (original) (raw)

BRIEF COMMUNICATION: LIVER

Association of Accelerometer-Measured Sedentary Behavior Patterns With Nonalcoholic Fatty Liver Disease Among Older Adults: The MIND-China Study

Han, Qi MD1,*; Han, Xiaolei MD, PhD1,2,*; Wang, Xiaojie MD1; Wang, Chaoqun MD1; Mao, Ming MD1; Tang, Shi MD, PhD2; Cong, Lin MD, PhD2; Hou, Tingting MD, PhD2; Liu, Cuicui MD2; Wang, Yongxiang MD, PhD2; Du, Yifeng MD, PhD1,2,†; Qiu, Chengxuan PhD1,3,†

1Department of Neurology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, P.R. China;

2Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P.R. China;

3Aging Research Center and Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden.

Correspondence: Yifeng Du, MD, PhD. E-mail: [email protected]. Yongxiang Wang, Email: [email protected].

SUPPLEMENTARY MATERIAL accompanies this paper at https://links.lww.com/AJG/C835

†Yifeng Du and Chengxuan Qiu shared senior authorship.

*Qi Han and Xiaolei Han contributed equally to this work.

Abstract

INTRODUCTION:

The relationships between sedentary behavior patterns and nonalcoholic fatty liver disease (NAFLD) in older adults are not well investigated.

METHODS:

This population-based study included 1,899 rural-dwelling adults (aged 60 years or older). We assessed sedentary parameters with ActiGraph and defined NAFLD using ultrasonography.

RESULTS:

Long total and prolonged sedentary time were associated with increased likelihoods of NAFLD, whereas engaging more breaks per sedentary hour and reallocating sedentary time to light-intensity physical activity were associated with reduced likelihoods of NAFLD (Plinear <0.05).

DISCUSSION:

Shorter sedentary time, engaging more frequent breaks in sedentary behavior, and replacing sedentary time with physical activity are associated with reduced likelihoods of NAFLD in older adults.