Effect of Gender on the Progression of Nondiabetic Renal... : Journal of the American Society of Nephrology (original) (raw)
Clinical Nephrology
A Meta-Analysis
Renal Division, Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York.
Correspondence to Dr. Joel Neugarten, Renal Laboratory, Montefiore Medical Center, 111 East 210 Street, Bronx, NY 10467. Phone: 718-920-4991; Fax: 718-920-6658.
Accepted July 31, 1999
Received May 24, 1999
Abstract
There is previously published evidence that male gender is associated with a more rapid rate of progression of nondiabetic chronic renal disease. However, some investigators have concluded that no such association exists. To help resolve this issue, a meta-analysis was performed using 68 studies that met defined criteria and contained a total of 11,345 patients to evaluate the effect of gender on the progression of nondiabetic chronic renal disease. The results indicate that men with chronic renal disease of various etiologies show a more rapid decline in renal function with time than do women.
Copyright © 2000 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
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