Combination Therapy of Angiotherapy, Radiation Therapy, and Radiofrequency Ablation for Pulmonary Metastasis of Hepatocellular Carcinoma Accompanied by Nontuberculous Mycobacteria (original) (raw)

Figure 1. CECT scan revealing well-defined, round masses (35 mm in the LUL and 10 mm in the RLL, each is marked with an arrow in the left and middle images) and enlarged subcarinal lymph node (arrow in the right image) with faint central calcification. (B) PET-CT performed one week after CECT showing increased FDG uptakes in the LUL mass and subcarinal lymph node. CECT, contrastenhanced computed tomography; LUL, left upper lobe; RLL, right lower lobe; PET-CT, positron emission tomography-computed tomography; FDG, fluorodeoxyglucose.

Figure 2. Follow-up CECT showing interval enlarged LUL mass (arrow in the left image) with heterogeneous contrast enhancement and internal lower densities, as well as an interval enlarged RLL mass (arrow in the middle image). Both lung masses appear suggestive of pulmonary metastasis. When compared with the initial CECT scan, interval increases in the sizes of mediastinal lymph nodes (arrow in the right image) can be seen. CECT, contrast-enhanced computed tomography; LUL, left upper lobe; RLL, right lower lobe.

Figure 3. Histopathology of the pulmonary metastasis. (A) H&E staining of the lung mass showing metastatic hepatocellular carcinoma (original magnification, ×200). (B) Tumor cells appear positive for hepatocyte-specific antigen (original magnification, ×200). H&E, hematoxylin and eosin.

Figure 4. (A) CECT performed one month after BAE showing that the size of the LUL mass (arrow) decreased from 44 mm to 40 mm. However, there an enhancing portion remained, suggesting viable foci. (B) CECT performed one month after radiotherapy showing that, in the LUL mass (arrow), the enhancing lesion elongated at the medial aspect. The size of the RLL mass increased from 15 mm to 17 mm. CECT, contrast-enhanced computed tomography; BAE, bronchial artery embolization; LUL, left upper lobe; RLL, right lower lobe.

Figure 5. (A) The left CECT scan was performed one month after RFA. Immediate follow-up CECT revealing an increase in the size of the RLL nodule. (B) Cone-beam CT was performed during the RFA procedure. Ground-glass opacity formed around the RLL mass. (C) The right CECT scan was performed three months after RFA. The size of the RLL mass decreased, and there was no viable portion in the mass. CECT, contrast-enhanced computed tomography; RFA, radiofrequency ablation; RLL, right lower lobe; CT, computed tomography.