Infections with Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae (original) (raw)

• Jacoby GA, Munoz-Price LS. The new beta-lactamases. N Engl J Med 2005 Jan 27; 352(4): 380–91
  Article PubMed CAS Google Scholar
• Paterson DL, Bonomo RA. Extended-spectrum betalactamases: a clinical update. Clin Microbiol Rev 2005 Oct; 18(4): 657–86
  Article PubMed CAS Google Scholar
• Nicolas-Chanoine MH, Jarlier V. Extended-spectrum beta-lactamases in long-term-care facilities. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1:111–6
  Article PubMed CAS Google Scholar
• Schwaber MJ, Navon-Venezia S, Kaye KS, et al. Clinical and economic impact of bacteremia with extended-spectrum-beta-lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2006 Apr; 50(4): 1257–62
  Article PubMed CAS Google Scholar
• Tumbarello M, Sanguinetti M, Montuori E, et al. Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment. Antimicrob Agents Chemother 2007 Jun; 51(6): 1987–94
  Article PubMed CAS Google Scholar
• Pitout JD, Nordmann P, Laupland KB, et al. Emergence of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) in the community. J Antimicrob Chemother 2005 Jul; 56(1): 52–9
  Article PubMed CAS Google Scholar
• Hawser SP, Bouchillon SK, Hoban DJ, et al. In vitro susceptibilities of aerobic and facultative anaerobic Gram-negative bacilli from patients with intra-abdominal infections worldwide from 2005–2007: results from the SMART study. Int J Antimicrob Agents 2009 Dec; 34(6): 585–8
  Article PubMed CAS Google Scholar
• Hawser SP, Bouchillon SK, Hoban DJ, et al. Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. Antimicrob Agents Chemother 2009 Aug; 53(8): 3280–4
  Article PubMed CAS Google Scholar
• Herzer PJ, Inouye S, Inouye M, et al. Phylogenetic distribution of branched RNA-linked multicopy single-stranded DNA among natural isolates of Escherichia coli J Bacteriol 1990 Nov; 172(11): 6175–81
  PubMed CAS Google Scholar
• Johnson JR, Delavari P, Kuskowski M, et al. Phylogenetic distribution of extraintestinal virulence-associated traits in Escherichia coli. J Infect Dis 2001 Jan 1; 183(1): 78–88
  Article PubMed CAS Google Scholar
• Canton R, Coque TM. The CTX-M beta-lactamase pandemic. Curr Opin Microbiol 2006 Oct; 9(5): 466–75
  Article PubMed CAS Google Scholar
• Talbot GH, Bradley J, Edwards Jr JE, et al. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis 2006 Mar 1; 42(5): 657–68
  Article PubMed Google Scholar
• Matsumoto Y, Ikeda F, Kamimura T, et al. Novel plasmid-mediated beta-lactamase from Escherichia coli that inactivates oxyimino-cephalosporins. Antimicrob Agents Chemother 1988 Aug; 32(8): 1243–6
  Article PubMed CAS Google Scholar
• Radice M, Power P, Di Conza J, et al. Early dissemination of CTX-M-derived enzymes in South America. Antimicrob Agents Chemother 2002 Feb; 46(2): 602–4
  Article PubMed CAS Google Scholar
• Pitout JD, Laupland KB. Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern. Lancet Infect Dis 2008 Mar; 8(3): 159–66
  Article PubMed CAS Google Scholar
• Rossolini GM, D’Andrea MM, Mugnaioli C. The spread of CTX-M-type extended-spectrum beta-lactamases. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 33–41
  Article Google Scholar
• Poirel L, Lartigue MF, Decousser JW, et al. ISEcp1B-mediated transposition of blaCTX-M in Escherichia coli. Antimicrob Agents Chemother 2005 Jan; 49(1): 447–50
  Article PubMed CAS Google Scholar
• Poirel L, Naas T, Nordmann P. Genetic support of extended-spectrum beta-lactamases. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 75–81
  Article Google Scholar
• Poirel L, Decousser JW, Nordmann P. Insertion sequence ISEcp1B is involved in expression and mobilization of a bla(CTX-M) beta-lactamase gene. Antimicrob Agents Chemother 2003 Sep; 47(9): 2938–45
  Article PubMed CAS Google Scholar
• Carattoli A. Resistance plasmid families in Enterobacteriaceae. Antimicrob Agents Chemother 2009 Jun; 53(6): 2227–38
  Article PubMed CAS Google Scholar
• Bonnet R. Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother 2004 Jan; 48(1): 1–14
  Article PubMed CAS Google Scholar
• Poirel L, Gniadkowski M, Nordmann P. Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum beta-lactamase CTX-M-15 and of its structurally related beta-lactamase CTX-M-3. J Antimicrob Chemother 2002 Dec; 50(6): 1031–4
  Article PubMed CAS Google Scholar
• Laupland KB, Church DL, Vidakovich J, et al. Community-onset extended-spectrum beta-lactamase (ESBL) producing Escherichia coli: importance of international travel. J Infect 2008 Dec; 57(6): 441–8
  Article PubMed Google Scholar
• Rodriguez-Bano J, Navarro MD. Extended-spectrum beta-lactamases in ambulatory care: a clinical perspective. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 104–10
  Article Google Scholar
• Pitout JD, Church DL, Gregson DB, et al. Molecular epidemiology of CTX-M-producing Escherichia coli in the Calgary Health Region: emergence of CTX-M-15-producing isolates. Antimicrob Agents Chemother 2007 Apr; 51(4): 1281–6
  Article PubMed CAS Google Scholar
• Karim A, Poirel L, Nagarajan S, et al. Plasmid-mediated extended-spectrum beta-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp 1. FEMS Microbiol Lett 2001 Jul 24; 201(2): 237–41
  PubMed CAS Google Scholar
• Novais A, Canton R, Moreira R, et al. Emergence and dissemination of Enterobacteriaceae isolates producing CTX-M-1-like enzymes in Spain are associated with IncFII (CTX-M-15) and broad-host-range (CTX-M-1, -3, and −32) plasmids. Antimicrob Agents Chemother 2007 Feb; 51(2): 796–9
  Article PubMed CAS Google Scholar
• Boyd DA, Tyler S, Christianson S, et al. Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob Agents Chemother 2004 Oct; 48(10): 3758–64
  Article PubMed CAS Google Scholar
• Robicsek A, Strahilevitz J, Jacoby GA, et al. Fluoro-quinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med 2006 Jan; 12(1): 83–8
  Article PubMed CAS Google Scholar
• Livermore DM, Canton R, Gniadkowski M, et al. CTX-M: changing the face of ESBLs in Europe. J Antimicrob Chemother 2007 Feb; 59(2): 165–74
  Article PubMed CAS Google Scholar
• Hawkey PM. Prevalence and clonality of extended-spectrum beta-lactamases in Asia. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 159–65
  Article PubMed CAS Google Scholar
• Lewis 2nd JS, Herrera M, Wickes B, et al. First report of the emergence of CTX-M-type extended-spectrum beta-lactamases (ESBLs) as the predominant ESBL isolated in a U.S. health care system. Antimicrob Agents Chemother 2007 Nov;51(11): 4015–21
  Article PubMed CAS Google Scholar
• Mulvey MR, Bryce E, Boyd D, et al. Ambler class A extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. in Canadian hospitals. Antimicrob Agents Chemother 2004 Apr; 48(4): 1204–14
  Article PubMed CAS Google Scholar
• Villegas MV, Kattan JN, Quinteros MG, et al. Prevalence of extended-spectrum beta-lactamases in South America. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 154–8
  Article Google Scholar
• Zong Z, Partridge SR, Thomas L, et al. Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool. Antimicrob Agents Chemother 2008 Nov; 52(11): 4198–202
  Article PubMed CAS Google Scholar
• Canton R, Novais A, Valverde A, et al. Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 144–53
  Article Google Scholar
• Ensor VM, Shahid M, Evans JT, et al. Occurrence, prevalence and genetic environment of CTX-M beta-lactamases in Enterobacteriaceae from Indian hospitals. J Antimicrob Chemother 2006 Dec; 58(6): 1260–3
  Article PubMed CAS Google Scholar
• Gupta V, Datta P. Extended-spectrum beta-lactamases (ESBL) in community isolates from North India: frequency and predisposing factors. Int J Infect Dis 2007 Jan; 11(1): 88–9
  Article PubMed Google Scholar
• Moubareck C, Daoud Z, Hakime NI, et al. Countrywide spread of community- and hospital-acquired extended-spectrum beta-lactamase (CTX-M-15)-producing Enterobacteriaceae in Lebanon. J Clin Microbiol 2005 Jul; 43(7): 3309–13
  Article PubMed CAS Google Scholar
• Blomberg B, Jureen R, Manji KP, et al. High rate of fatal cases of pediatric septicemia caused by gram-negative bacteria with extended-spectrum beta-lactamases in Dar es Salaam, Tanzania. J Clin Microbiol 2005 Feb; 43(2): 745–9
  Article PubMed Google Scholar
• Gangoue-Pieboji J, Miriagou V, Vourli S, et al. Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element. Antimicrob Agents Chemother 2005 Jan; 49(1): 441–3
  Article PubMed CAS Google Scholar
• Mamlouk K, Boutiba-Ben Boubaker I, Gautier V, et al. Emergence and outbreaks of CTX-M beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae strains in a Tunisian hospital. J Clin Microbiol 2006 Nov; 44(11): 4049–56
  Article PubMed CAS Google Scholar
• Touati A, Benallaoua S, Djoudi F, et al. Characterization of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from hospital environments in Algeria. Microb Drug Resist 2007 Summer; 13(2): 85–9
  Article PubMed CAS Google Scholar
• Bush K. Extended-spectrum beta-lactamases in North America, 1987–2006. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 134–43
  Article PubMed CAS Google Scholar
• Moland ES, Black JA, Hossain A, et al. Discovery of CTX-M-like extended-spectrum beta-lactamases in Escherichia coli isolates from five US States. Antimicrob Agents Chemother 2003 Jul; 47(7): 2382–3
  Article PubMed CAS Google Scholar
• Castanheira M, Mendes RE, Rhomberg PR, et al. Rapid emergence of blaCTX-M among Enterobacteriaceae in U.S. Medical Centers: molecular evaluation from the MYSTIC Program (2007). Microb Drug Resist 2008 Sep; 14(3): 211–6
  Article PubMed CAS Google Scholar
• Pitout JD, Laupland KB, Church DL, et al. Virulence factors of Escherichia coli isolates that produce CTX-M-type extended-spectrum beta-lactamases. Antimicrob Agents Chemother 2005 Nov; 49(11): 4667–70
  Article PubMed CAS Google Scholar
• Pallecchi L, Malossi M, Mantella A, et al. Detection of CTX-M-type beta-lactamase genes in fecal Escherichia coli isolates from healthy children in Bolivia and Peru. Antimicrob Agents Chemother 2004 Dec; 48(12): 4556–61
  Article PubMed CAS Google Scholar
• Valenzuela de Silva EM, Mantilla Anaya JR, Reguero Reza MT, et al. Detection of CTX-M-1, CTX-M-15, and CTX-M-2 in clinical isolates of Enterobacteriaceae in Bogota, Colombia. J Clin Microbiol 2006 May; 44(5): 1919–20
  Article PubMed CAS Google Scholar
• Edelstein M, Pimkin M, Palagin I, et al. Prevalence and molecular epidemiology of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals. Antimicrob Agents Chemother 2003 Dec; 47(12): 3724–32
  Article PubMed CAS Google Scholar
• Woodford N, Ward ME, Kaufmann ME, et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother 2004 Oct; 54(4): 735–43
  Article PubMed CAS Google Scholar
• Oteo J, Navarro C, Cercenado E, et al. Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions. J Clin Microbiol 2006 Jul; 44(7): 2359–66
  Article PubMed CAS Google Scholar
• Eisner A, Fagan EJ, Feierl G, et al. Emergence of Enterobacteriaceae isolates producing CTX-M extended-spectrum beta-lactamase in Austria. Antimicrob Agents Chemother 2006 Feb; 50(2): 785–7
  Article PubMed CAS Google Scholar
• Mugnaioli C, Luzzaro F, De Luca F, et al. CTX-M-type extended-spectrum beta-lactamases in Italy: molecular epidemiology of an emerging countrywide problem. Antimicrob Agents Chemother 2006 Aug; 50(8): 2700–6
  Article PubMed CAS Google Scholar
• Mendonca N, Leitao J, Manageiro V, et al. Spread of extended-spectrum beta-lactamase CTX-M-producing Escherichia coli clinical isolates in community and noso-comial environments in Portugal. Antimicrob Agents Chemother 2007 Jun; 51(6): 1946–55
  Article PubMed CAS Google Scholar
• Galas M, Decousser JW, Breton N, et al. Nationwide study of the prevalence, characteristics, and molecular epidemiology of extended-spectrum-beta-lactamase-producing Enterobacteriaceae in France. Antimicrob Agents Chemother 2008 Feb; 52(2): 786–9
  Article PubMed CAS Google Scholar
• Fang H, Ataker F, Hedin G, et al. Molecular epidemiology of extended-spectrum beta-lactamases among Escherichia coli isolates collected in a Swedish hospital and its associated health care facilities from 2001 to 2006. J Clin Microbiol 2008 Feb; 46(2): 707–12
  Article PubMed CAS Google Scholar
• Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995 Sep; 33(9): 2233–9
  PubMed CAS Google Scholar
• Lavollay M, Mamlouk K, Frank T, et al. Clonal dissemination of a CTX-M-15 beta-lactamase-producing Escherichia coli strain in the Paris area, Tunis, and Bangui. Antimicrob Agents Chemother 2006 Jul; 50(7): 2433–8
  Article PubMed CAS Google Scholar
• Gonullu N, Aktas Z, Kayacan CB, et al. Dissemination of CTX-M-15 beta-lactamase genes carried on Inc FI and FII plasmids among clinical isolates of Escherichia coli in a university hospital in Istanbul, Turkey. J Clin Microbiol 2008 Mar; 46(3): 1110–2
  Article PubMed CAS Google Scholar
• Marcade G, Deschamps C, Boyd A, et al. Replicon typing of plasmids in Escherichia coli producing extended-spectrum beta-lactamases. J Antimicrob Chemother 2009 Jan; 63(1): 67–71
  Article PubMed CAS Google Scholar
• Coque TM, Novais A, Carattoli A, et al. Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15. Emerg Infect Dis 2008 Feb; 14(2): 195–200
  Article PubMed CAS Google Scholar
• Nicolas-Chanoine MH, Blanco J, Leflon-Guibout V, et al. Intercontinental emergence of Escherichia coli clone O25: H4-ST131 producing CTX-M-15. J Antimicrob Chemother 2008 Feb; 61(2): 273–81
  Article PubMed CAS Google Scholar
• Sullivan CB, Diggle MA, Clarke SC. Multilocus sequence typing: data analysis in clinical microbiology and public health. Mol Biotechnol 2005 Mar; 29(3): 245–54
  Article PubMed CAS Google Scholar
• Lau SH, Cheesborough J, Kaufmann ME, et al. Rapid identification of uropathogenic Escherichia coli of the O25:H4-ST131 clonal lineage using the DiversiLab repetitive sequence-based PCR system. Clin Microbiol Infect. Epub 2009 Mar 21
• Pitout JD, Campbell L, Church DL, et al. Using a commercial DiversiLab semiautomated repetitive sequence-based PCR typing technique for identification of Escherichia coli clone ST131 producing CTX-M-15. J Clin Microbiol 2009 Apr; 47(4): 1212–5
  Article PubMed CAS Google Scholar
• Clermont O, Dhanji H, Upton M, et al. Rapid detection of the O25b-ST131 clone of Escherichia coli encompassing the CTX-M-15-producing strains. J Antimicrob Chemother 2009 Aug; 64(2): 274–7
  Article PubMed CAS Google Scholar
• Johnson JR, Menard M, Johnston B, et al. Epidemic clonal groups of Escherichia coli as a cause of antimicrobialresistant urinary tract infections in Canada, 2002 to 2004. Antimicrob Agents Chemother 2009 Jul; 53(7): 2733–9
  Article PubMed CAS Google Scholar
• Blanco M, Alonso MP, Nicolas-Chanoine MH, et al. Molecular epidemiology of Escherichia coli producing extended-spectrum ta-lactamases in Lugo (Spain): dissemination of clone O25b:H4-ST131 producing CTX-M-15. J Antimicrob Chemother 2009 Jun; 63(6): 1135–41
  Article PubMed CAS Google Scholar
• Lau SH, Kaufmann ME, Livermore DM, et al. UK epidemic Escherichia coli strains A-E, with CTX-M-15 betalactamase, all belong to the international O25:H4-ST131 clone. J Antimicrob Chemother 2008 Dec; 62(6): 1241–4
  Article PubMed CAS Google Scholar
• Cagnacci S, Gualco L, Debbia E, et al. European emergence of ciprofloxacin-resistant Escherichia coli clonal groups O25:H4-ST 131 and O15:K52:H1 causing community-acquired uncomplicated cystitis. J Clin Microbiol 2008 Aug; 46(8): 2605–12
  Article PubMed CAS Google Scholar
• Yumuk Z, Afacan G, Nicolas-Chanoine MH, et al. Turkey: a further country concerned by community-acquired E_scherichia_ c_oli_ clone O25-ST131 producing CTX-M-15. J Antimicrob Chemother 2008 Aug; 62(2): 284–8
  Article PubMed CAS Google Scholar
• Literacka E, Bedenic B, Baraniak A, et al. blaCTX-M genes in E_scherichia_ c_oli_ strains from Croatian hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a, blaCTX-M-15) genetic structures. Antimicrob Agents Chemother 2009; 53(4): 1630–5
  Article PubMed CAS Google Scholar
• Suzuki S, Shibata N, Yamane K, et al. Change in the prevalence of extended-spectrum-beta-lactamase-producing E_scherichia_ c_oli_ in Japan by clonal spread. J Antimicrob Chemother 2009 Jan; 63(1): 72–9
  Article PubMed CAS Google Scholar
• Johnson JR, Johnston BD, Jorgensen JH, et al., editors. CTX-M-15-producing E_._ c_oli_ in the United States: predominance of sequence type ST131 (O25:H4). Proceedings of the Forty-eighth Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington (DC): American Society for Microbiology, 2008
• Naseer U, Haldorsen B, Tofteland S, et al. Molecular characterization of CTX-M-15-producing clinical isolates of E_scherichia_ c_oli_ reveals the spread of multidrug-resistant ST131 (O25:H4) and ST964 (O102:H6) strains in Norway. APMIS 2009 Jul; 117(7): 526–36
  Article PubMed CAS Google Scholar
• Leflon-Guibout V, Blanco J, Amaqdouf K, et al. Absence of CTX-M enzymes but high prevalence of clones, including clone ST131, among fecal E_scherichia_ c_oli_ isolates from healthy subjects living in the area of Paris, France. J Clin Microbiol 2008 Dec; 46(12): 3900–5
  Article PubMed CAS Google Scholar
• Arpin C, Quentin C, Grobost F, et al. Nationwide survey of extended-spectrum ta-lactamase-producing Enterobacteriaceae in the French community setting. J Antimicrob Chemother 2009 Jun; 63(6): 1205–14
  Article PubMed CAS Google Scholar
• Oteo J, Diestra K, Juan C, et al. Extended-spectrum betalactamase-producing E_scherichia_ c_oli_ in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex/A, ST23 complex/A and ST131/B2. Int J Antimicrob Agents 2009 Aug; 34(2): 173–6
  Article PubMed CAS Google Scholar
• Rooney PJ, O’Leary MC, Loughrey AC, et al. Nursing homes as a reservoir of extended-spectrum ta-lactamase (ESBL)-producing ciprofloxacin-resistant E_scherichia_ c_oli._ J Antimicrob Chemother 2009 Sep; 64(3): 635–41
  Article PubMed CAS Google Scholar
• Pomba C, da Fonseca JD, Baptista BC, et al. Detection of the pandemic O25-ST131 human virulent E_scherichia_ c_oli_ CTX-M-15-producing clone harboring the qnrB2 and aac(6′)-Ib-cr genes in a dog. Antimicrob Agents Chemother 2009 Jan; 53(1): 327–8
  Article PubMed CAS Google Scholar
• Freeman JT, McBride SJ, Heffernan H, et al. Community-onset genitourinary tract infection due to CTX-M-15-producing E_scherichia_ c_oli_ among travelers to the Indian subcontinent in New Zealand. Clin Infect Dis 2008 Sep 1; 47(5): 689–92
  Article PubMed Google Scholar
• Pitout JD, Campbell L, Church DL, et al. Molecular characteristics of travel-related extended-spectrum-beta-lactamase-producing E_scherichia_ c_oli_ isolates from the Calgary Health Region. Antimicrob Agents Chemother 2009 Jun; 53(6): 2539–43
  Article PubMed CAS Google Scholar
• Pitout JD, Gregson DB, Campbell L, et al. Molecular characteristics of extended-spectrum-beta-lactamase-producing E_scherichia_ c_oli_ isolates causing bacteremia in the Calgary Health Region from 2000 to 2007: emergence of clone ST131 as a cause of community-acquired infections. Antimicrob Agents Chemother 2009 Jul; 53(7): 2846–51
  Article PubMed CAS Google Scholar
• Lee SY, Kotapati S, Kuti JL, et al. Impact of extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_ and K_lebsiella_ species on clinical outcomes and hospital costs: a matched cohort study. Infect Control Hosp Epidemiol 2006 Nov; 27(11): 1226–32
  Article PubMed Google Scholar
• Lautenbach E, Patel JB, Bilker WB, et al. Extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_ and K_lebsiella_ p_neumoniae:_ risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 2001 Apr 15; 32(8): 1162–71
  Article PubMed CAS Google Scholar
• Paterson DL, Ko WC, Von Gottberg A, et al. Antibiotic therapy for K_lebsiella_ p_neumoniae_ bacteremia: implications of production of extended-spectrum beta-lactamases. Clin Infect Dis 2004 Jul 1; 39(1): 31–7
  Article PubMed CAS Google Scholar
• Schwaber MJ, Carmeli Y. Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis. J Antimicrob Chemother 2007 Nov; 60(5): 913–20
  Article PubMed CAS Google Scholar
• Giske CG, Monnet DL, Cars O, et al. Clinical and economic impact of common multidrug-resistant gramnegative bacilli. Antimicrob Agents Chemother 2008 Mar; 52(3): 813–21
  Article PubMed CAS Google Scholar
• Maragakis LL, Perencevich EN, Cosgrove SE. Clinical and economic burden of antimicrobial resistance. Expert Rev Anti Infect Ther 2008 Oct; 6(5): 751–63
  Article PubMed Google Scholar
• Slama TG. Gram-negative antibiotic resistance: there is a price to pay. Crit Care 2008; 12 Suppl. 4: S4
  Article PubMed Google Scholar
• Peterson LR. Antibiotic policy and prescribing strategies for therapy of extended-spectrum beta-lactamase-producing Enterobacteriaceae: the role of piperacillin-tazobactam. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 181–4
  Article Google Scholar
• Lopez-Cerero L, Picon E, Morillo C, et al. Comparative assessment of inoculum effects on the antimicrobial activity of amoxycillin-clavulanate and piperacillin-tazobactam with extended-spectrum beta-lactamase-producing and extended-spectrum beta-lactamase-non-producing E_scherichia_ c_oli_ isolates. Clin Microbiol Infect. Epub 2009 Jul 15
• Thomson KS, Moland ES. Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2001 Dec; 45(12): 3548–54
  Article PubMed CAS Google Scholar
• Pangon B, Bizet C, Bure A, et al. I_n_ v_ivo_ selection of a cephamycin-resistant, porin-deficient mutant o_f_ K_lebsiella_ p_neumoniae_ producing a TEM-3 beta-lactamase. J Infect Dis 1989 May; 159(5): 1005–6
  Article PubMed CAS Google Scholar
• Paterson DL. Recommendation for treatment of severe infections caused by Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs). Clin Microbiol Infect 2000 Sep; 6(9): 460–3
  Article PubMed CAS Google Scholar
• del Mar Tomas M, Cartelle M, Pertega S, et al. Hospital outbreak caused by a carbapenem-resistant strain of A_cinetobacter_ baumannii: patient prognosis and risk-factors for colonisation and infection. Clin Microbiol Infect 2005 Jul; 11(7): 540–6
  Article PubMed Google Scholar
• Clinical Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: 18th informational supplement (CLSI document M100-S18). Wayne (PA): Clinical Laboratory Standards Institute, 2008
  Google Scholar
• Szabo D, Silveira F, Hujer AM, et al. Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in E_nterobacter_ c_loacae_. Antimicrob Agents Chemother 2006 Aug; 50(8): 2833–5
  Article PubMed CAS Google Scholar
• Garau J. Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline. Clin Microbiol Infect 2008 Jan; 14 Suppl. 1: 198–202
  Article Google Scholar
• Morosini MI, Garcia-Castillo M, Coque TM, et al. Antibiotic coresistance in extended-spectrum-beta-lactamase-producing Enterobacteriaceae and i_n_ v_itro_ activity of tigecycline. Antimicrob Agents Chemother 2006 Aug; 50(8): 2695–9
  Article PubMed CAS Google Scholar
• Pitout JD, Le P, Church DL, et al. Antimicrobial susceptibility of well-characterised multiresistant CTX-M-producing E_scherichia_ c_oli:_ failure of automated systems to detect resistance to piperacillin/tazobactam. Int J Antimicrob Agents 2008 Oct; 32(4): 333–8
  Article PubMed CAS Google Scholar
• Puerto AS, Fernandez JG, del Castillo D, et al. I_n_ v_itro_ activity of beta-lactam and non-beta-lactam antibiotics in extended-spectrum beta-lactamase-producing clinical isolates of E_scherichia_ c_oli_. Diagn Microbiol Infect Dis 2006 Feb; 54(2): 135–9
  Article PubMed CAS Google Scholar
• Endimiani A, Luzzaro F, Perilli M, et al. Bacteremia due to K_lebsiella_ p_neumoniae_ isolates producing the TEM-52 extended-spectrum beta-lactamase: treatment outcome of patients receiving imipenem or ciprofloxacin. Clin Infect Dis 2004 Jan 15; 38(2): 243–51
  Article PubMed CAS Google Scholar
• Wong-Beringer A, Hindler J, Loeloff M, et al. Molecular correlation for the treatment outcomes in bloodstream infections caused by E_scherichia_ c_oli_ and K_lebsiella_ p_neumoniae_ with reduced susceptibility to ceftazidime. Clin Infect Dis 2002 Jan 15; 34(2): 135–46
  Article PubMed CAS Google Scholar
• Bassetti M, Righi E, Fasce R, et al. Efficacy of ertapenem in the treatment of early ventilator-associated pneumonia caused by extended-spectrum beta-lactamase-producing organisms in an intensive care unit. J Antimicrob Chemother 2007 Aug; 60(2): 433–5
  Article PubMed CAS Google Scholar
• Oteo J, Delgado-Iribarren A, Vega D, et al. Emergence of imipenem resistance in clinical E_scherichia_ c_oli_ during therapy. Int J Antimicrob Agents 2008 Dec; 32(6): 534–7
  Article PubMed CAS Google Scholar
• Skurnik D, Lasocki S, Bremont S, et al. Development of ertapenem resistance in a patient with mediastinitis caused by an extended-spectrum beta-lactamase producing K_lebsiella_ p_neumoniae._ J Med Microbiol. Epub 2009 Sep 10
• Doumith M, Ellington MJ, Livermore DM, et al. Molecular mechanisms disrupting porin expression in ertapenem-resistant K_lebsiella_ and Enterobacter spp. clinical isolates from the UK. J Antimicrob Chemother 2009 Apr; 63(4): 659–67
  Article PubMed CAS Google Scholar
• Leavitt A, Chmelnitsky I, Colodner R, et al. Ertapenem resistance among extended-spectrum-beta-lactamase-producing K_lebsiella_ p_neumoniae_ isolates. J Clin Microbiol 2009 Apr; 47(4): 969–74
  Article PubMed CAS Google Scholar
• MacGowan AP, Bowker KE, Noel AR. Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an i_n_ v_itro_ pharmacokinetic model of S_taphylococcus_ a_ureus_ infection. Antimicrob Agents Chemother 2008 Apr; 52(4): 1401–6
  Article PubMed CAS Google Scholar
• Du B, Long Y, Liu H, et al. Extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_ and K_lebsiella_ p_neumoniae_ bloodstream infection: risk factors and clinical outcome. Intensive Care Med 2002 Dec; 28(12): 1718–23
  Article PubMed Google Scholar
• Bin C, Hui W, Renyuan Z, et al. Outcome of cephalosporin treatment of bacteremia due to CTX-M-type extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_. Diagn Microbiol Infect Dis 2006 Dec; 56(4): 351–7
  Article PubMed CAS Google Scholar
• Jones RN, Biedenbach DJ, Gales AC. Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against E_nterobacter_ spp. and ESBL-producing K_lebsiella_ spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997–2000). Int J Antimicrob Agents 2003 Jan; 21(1): 1–7
  Article PubMed CAS Google Scholar
• Ramphal R, Ambrose PG. Extended-spectrum beta-lactamases and clinical outcomes: current data. Clin Infect Dis 2006 Apr 15; 42 Suppl. 4: S164–72
  Article PubMed CAS Google Scholar
• Zanetti G, Bally F, Greub G, et al. Cefepime versus imipenem-cilastatin for treatment of nosocomial pneumonia in intensive care unit patients: a multicenter, evaluator-blind, prospective, randomized study. Antimicrob Agents Chemother 2003 Nov; 47(11): 3442–7
  Article PubMed CAS Google Scholar
• Lee CH, Su LH, Tang YF, et al. Treatment of ESBL-producing K_lebsiella_ p_neumoniae_ bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates. J Antimicrob Chemother 2006 Nov; 58(5): 1074–7
  Article PubMed CAS Google Scholar
• Tumbarello M, Spanu T, Sanguinetti M, et al. Bloodstream infections caused by extended-spectrum-beta-lactamaseproducing K_lebsiella_ p_neumoniae:_ risk factors, molecular epidemiology, and clinical outcome. Antimicrob Agents Chemother 2006 Feb; 50(2): 498–504
  Article PubMed CAS Google Scholar
• Gavin PJ, Suseno MT, Thomson Jr RB, et al. Clinical correlation of the CLSI susceptibility breakpoint for piperacillin-tazobactam against extended-spectrum-beta-lactamase-producing E_scherichia_ c_oli_ and K_lebsiella_ species. Antimicrob Agents Chemother 2006 Jun; 50(6): 2244–7
  Article PubMed CAS Google Scholar
• Rodríguez-Baño J, Navarro MD, Romero L, et al. Bacteremia due to extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_ in the CTX-M era: a new clinical challenge. Clin Infect Dis 2006 Dec 1; 43(11): 1407–14
  Article PubMed Google Scholar
• Rodríguez-Baño J, Alcala JC, Cisneros JM, et al. Community infections caused by extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_. Arch Intern Med 2008 Sep 22; 168(17): 1897–902
  Article PubMed Google Scholar
• Lagace-Wiens PR, Nichol KA, Nicolle LE, et al. Treatment of lower urinary tract infection caused by multidrug-resistant extended-spectrum-beta-lactamase-producing E_scherichia_ c_oli_ with amoxicillin/clavulanate: case report and characterization of the isolate. J Antimicrob Chemo-ther 2006 Jun; 57(6): 1262–3
  Article CAS Google Scholar
• Kim YK, Pai H, Lee HJ, et al. Bloodstream infections by extended-spectrum beta-lactamase-producing E_scherichia_ c_oli_ and K_lebsiella_ p_neumoniae_ in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 2002 May; 46(5): 1481–91
  Article PubMed CAS Google Scholar
• Pitout JD. Multiresistant Enterobacteriaceae: new threat of an old problem. Expert Rev Anti Infect Ther 2008 Oct; 6(5): 657–69
  Article PubMed CAS Google Scholar
• de Cueto M, Hernandez JR, Lopez-Cerero L, et al. Activity of fosfomycin against extended-spectrum beta-lactamase producing E_scherichia_ c_oli_ and K_lebsiella_ p_neumoniae_. Enferm Infecc Microbiol Clin 2006 Dec; 24(10): 613–6
  Article PubMed Google Scholar
• Galatti L, Sessa A, Mazzaglia G, et al. Antibiotic prescribing for acute and recurrent cystitis in primary care: a 4 year descriptive study. J Antimicrob Chemother 2006 Mar; 57(3): 551–6
  Article PubMed CAS Google Scholar
• Oteo J, Orden B, Bautista V, et al. CTX-M-15-producing urinary E_scherichia_ c_oli_ O25b-ST131-phylogroup B2 has acquired resistance to fosfomycin. J Antimicrob Chemother 2009 Oct; 64(4): 712–7
  Article PubMed CAS Google Scholar
• Falagas ME, Karageorgopoulos DE, Dimopoulos G. Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of tigecycline. Curr Drug Metab 2009 Jan; 10(1): 13–21
  Article PubMed CAS Google Scholar
• Zahar JR, Lortholary O, Martin C, et al. Addressing the challenge of extended-spectrum beta-lactamases. Curr Opin Investig Drugs 2009 Feb; 10(2): 172–80
  PubMed CAS Google Scholar
• Livermore DM, Tulkens PM. Temocillin revived. J Antimicrob Chemother 2009 Feb; 63(2): 243–5
  Article PubMed CAS Google Scholar
• Glupczynski Y, Huang TD, Berhin C, et al. I_n_ v_itro_ activity of temocillin against prevalent extended-spectrum beta-lactamases producing Enterobacteriaceae from Belgian intensive care units. Eur J Clin Microbiol Infect Dis 2007 Nov; 26(11): 777–83
  Article PubMed CAS Google Scholar
• Barton E, Flanagan P, Hill S. Spinal infection caused by ESBL-producing K_lebsiella_ pneumoniae treated with temocillin. J Infect 2008 Oct; 57(4): 347–9
  Article PubMed Google Scholar
• Nicolle LE, Mulvey MR. Successful treatment of CTX-M ESBL producing E_scherichia_ c_oli_ relapsing pyelonephritis with long term pivmecillinam. Scand J Infect Dis 2007; 39(8): 748–9
  Article PubMed CAS Google Scholar