Routine Screening for CKD Should Be Done in Asymptomatic... : Clinical Journal of the American Society of Nephrology (original) (raw)
Public Policy Series
Routine Screening for CKD Should Be Done in Asymptomatic Adults … Selectively
Renal, Electrolyte, and Hypertension Division, Perelman School of Medicine of the University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Correspondence: Dr. Jeffrey S. Berns, Renal, Electrolyte, and Hypertension Division, Perelman School of Medicine of the University of Pennsylvania, Hospital of the University of Pennsylvania, 3400 Spruce Street, 1 Founders Pavilion, Philadelphia, PA 19104. Email: [email protected]
Abstract
CKD is an important public health problem associated with substantial morbidity, impaired quality of life, shortened life expectancy, and excessive health care costs. Given its long preclinical latency, screening of asymptomatic individuals for CKD has been considered as a potentially useful means of early detection, with a goal of reducing CKD progression and its complications. A recent clinical practice guideline from the American College of Physicians that recommended against screening for CKD in asymptomatic adults without risk factors has reignited debate regarding CKD screening. Despite the lack of randomized controlled trial evidence showing benefits of CKD screening, even among individuals at increased risk for CKD, such as those with diabetes or hypertension or who are of certain high-risk racial or ethnic groups, a thoughtful and selective approach to CKD screening seems to be cost-effective and clinically valuable. CKD screening is recommended by several nephrology professional societies and appropriate in at-risk asymptomatic individuals with the intent of identifying and managing CKD, diagnosing the etiology of CKD, limiting or preventing CKD progression and its associated cardiovascular disease risk, and minimizing risk of AKI, inappropriate drug dosing, and nephrotoxic injury.
Copyright © 2014 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
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