TRIENNIAL GROWTH SYMPOSIUM: Important roles for L-glutamine in swine nutrition and production1,2 (original) (raw)

Journal Article

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

,

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

Search for other works by this author on:

*Departments of Animal Science and of Veterinary Integrative Biosciences, Texas A&M University, College Station 77843

†State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, China 100193

Search for other works by this author on:

Received:

19 October 2010

Accepted:

08 December 2010

• • Article contents
  • Figures & tables
  • Video
  • Audio
  • Supplementary Data
• Cite

Cite

G. Wu, F. W. Bazer, G. A. Johnson, D. A. Knabe, R. C. Burghardt, T. E. Spencer, X. L. Li, J. J. Wang, TRIENNIAL GROWTH SYMPOSIUM: Important roles for L-glutamine in swine nutrition and production,, Journal of Animal Science, Volume 89, Issue 7, July 2011, Pages 2017–2030, https://doi.org/10.2527/jas.2010-3614
Close

Navbar Search Filter Mobile Enter search term Search

ABSTRACT

L-Glutamine (Gln) has traditionally not been considered a nutrient needed in diets for livestock species or even mentioned in classic animal nutrition textbooks. This is due to previous technical difficulties in Gln analysis and the unsubstantiated assumption that animals can synthesize sufficient amounts of Gln to meet their needs. Consequently, the current (1998) version of NRC does not recommend dietary Gln requirements for swine. This lack of knowledge about Gln nutrition has contributed to suboptimal efficiency of global pig production. Because of recent advances in research, Gln is now known to be an abundant AA in physiological fluids and proteins and a key regulator of gene expression. Additionally, Gln can regulate cell signaling via the mammalian target of rapamycin pathway, adenosine monophosphate-activated protein kinase, extracellular signal-related kinase, Jun kinase, mitogen-activated protein kinase, and nitric oxide. The exquisite integration of Gln-dependent regulatory networks has profound effects on cell proliferation, differentiation, migration, metabolism, homeostasis, survival, and function. As a result of translating basic research into practice, dietary supplementation with 1% Gln maintains gut health and prevents intestinal dysfunction in low-birth-weight or early-weaned piglets while increasing their growth performance and survival. In addition, supplementing 1% Gln to a corn- and soybean-meal-based diet between d 90 and 114 of gestation ameliorates fetal growth retardation in gilts and reduces preweaning mortality of piglets. Furthermore, dietary supplementation with 1% Gln enhances milk production by lactating sows. Thus, adequate amounts of dietary Gln, a major nutrient, are necessary to support the maximum growth, development, and production performance of swine.

© American Society of Animal Science 2011

You do not currently have access to this article.

Personal account

• Sign in with email/username & password
• Get email alerts
• Save searches
• Purchase content
• Activate your purchase/trial code
• Add your ORCID iD

Get help with access

Institutional access

Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. If you are a member of an institution with an active account, you may be able to access content in one of the following ways:

IP based access

Typically, access is provided across an institutional network to a range of IP addresses. This authentication occurs automatically, and it is not possible to sign out of an IP authenticated account.

Sign in through your institution

Choose this option to get remote access when outside your institution. Shibboleth/Open Athens technology is used to provide single sign-on between your institution’s website and Oxford Academic.

1. Click Sign in through your institution.
2. Select your institution from the list provided, which will take you to your institution's website to sign in.
3. When on the institution site, please use the credentials provided by your institution. Do not use an Oxford Academic personal account.
4. Following successful sign in, you will be returned to Oxford Academic.

If your institution is not listed or you cannot sign in to your institution’s website, please contact your librarian or administrator.

Sign in with a library card

Enter your library card number to sign in. If you cannot sign in, please contact your librarian.

Society Members

Society member access to a journal is achieved in one of the following ways:

Sign in through society site

Many societies offer single sign-on between the society website and Oxford Academic. If you see ‘Sign in through society site’ in the sign in pane within a journal:

1. Click Sign in through society site.
2. When on the society site, please use the credentials provided by that society. Do not use an Oxford Academic personal account.
3. Following successful sign in, you will be returned to Oxford Academic.

If you do not have a society account or have forgotten your username or password, please contact your society.

Sign in using a personal account

Some societies use Oxford Academic personal accounts to provide access to their members. See below.

Personal account

A personal account can be used to get email alerts, save searches, purchase content, and activate subscriptions.

Some societies use Oxford Academic personal accounts to provide access to their members.

Viewing your signed in accounts

Click the account icon in the top right to:

• View your signed in personal account and access account management features.
• View the institutional accounts that are providing access.

Signed in but can't access content

Oxford Academic is home to a wide variety of products. The institutional subscription may not cover the content that you are trying to access. If you believe you should have access to that content, please contact your librarian.

Institutional account management

For librarians and administrators, your personal account also provides access to institutional account management. Here you will find options to view and activate subscriptions, manage institutional settings and access options, access usage statistics, and more.

Purchase

Short-term Access

To purchase short-term access, please sign in to your personal account above.

Don't already have a personal account? Register

TRIENNIAL GROWTH SYMPOSIUM: Important roles for L-glutamine in swine nutrition and production1,2 - 24 Hours access

EUR €38.00

GBP £33.00

USD $41.00

Rental

This article is also available for rental through DeepDyve.

Citations

Views

Altmetric

Metrics

Total Views 787

504 Pageviews

283 PDF Downloads

Since 1/1/2018

Citations

184 Web of Science

×

Email alerts

Citing articles via

• Latest

• Most Read

• Most Cited

More from Oxford Academic