Sepsis associated encephalopathy (SAE): a review (original) (raw)

IMR Press / FBL / Volume 9 / Issue 2 / DOI: 10.2741/1250

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Article

Sepsis associated encephalopathy (SAE): a review

Affiliation

1 Critical Care Medicine, Louisiana State University Health Sciences CenterShreveport, Shreveport, LA

2 Department of Neurology, and Medicine, Louisiana State University Health Sciences CenterShreveport, Shreveport, LA

Abstract

Sepsis associated encephalopathy (SAE) is a poorly understood condition that is associated with severe sepsis and appears to have a negative influence on survival. The incidence of encephalopathy secondary to sepsis is unknown. Amino acid derangements, blood-brain barrier disruption, abnormal neurotransmitters, and direct CNS effect are possible causes of septic encephalopathy. Research has not defined the pathogenesis of SAE.

Keywords

Sepsis

Encephalopathy

Shock

Septic Shock

Altered Mental Status

Review

Front. Biosci. (Landmark Ed) Print ISSN 2768-6701 Electronic ISSN 2768-6698

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