Transcriptome Analysis of Single Cells (original) (raw)

29.4K Views

07:27 min

April 25th, 2011

DOI :

10.3791/2634-v

April 25th, 2011

29,450 Views


Jacqueline Morris*1, Jennifer M. Singh*1, James H. Eberwine1,2

1Department of Pharmacology, University of Pennsylvania, 2The Penn Genome Frontiers Institute, University of Pennsylvania

0:05

Title

1:11

Preparing Culture and Pipettes

1:53

Harvesting Cells

5:04

Saving the Cell

6:07

Representative Results for Single Cell Harvest and aRNA Analysis

7:08

Conclusion

In this article we describe a simple method for the harvesting of single cells from rat primary neuronal cultures and subsequent transcriptome analysis using aRNA amplification. This approach is generalizable to any cell type.

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