Endocrinology and Metabolism (original) (raw)

Fig. 1Mortality of coronavirus disease 2019 (COVID-19) patients according to (A) diabetes mellitus (DM), (B) fibrosis-4 (FIB-4) index, and (C) diabetes mellitus (DM) and FIB-4 index. (A) Red line, patients with diabetes; blue line, patients without diabetes. (B) Red line, patients with high FIB-4 index; blue line, patients with low FIB-4 index. (C) Red solid line, patents with diabetes and high FIB-4 index; red dashed line, non-diabetes patients with high FIB-4 index; blue solid line, patents with diabetes and low FIB-4 index; blue dashed line, non-diabetes patients with low FIB-4 index. Data were analyzed using Cox proportional hazards model and all data are expressed as hazard ratio (HR) (95% confidence interval). Model was adjusted for age, sex, and underlying diseases.

Fig. 2Mortality of coronavirus disease 2019 (COVID-19) according to the presence of diabetes mellitus (DM) in patient (A) with low fibrosis-4 (FIB-4) index and (B) with high FIB-4 index. Red line, patients with diabetes; blue line, patients without diabetes. Data were analyzed using Cox proportional hazards model and all data are expressed as hazard ratio (HR) (95% confidence interval). Model was adjusted for age, sex, and underlying diseases.

Fig. 3Mortality of coronavirus disease 2019 (COVID-19) according to fibrosis-4 (FIB-4) index in patient (A) without diabetes mellitus (DM) and (B) with DM. Red line, patients with high FIB-4 index; blue line, patients with low FIB-4 index. Data were analyzed using Cox proportional hazards model all data are expressed as hazard ratio (HR) (95% confidence interval). Model was adjusted for age, sex, and underlying diseases.

Fig. 4Odds ratio (OR) of severe clinical course (A) and severe clinical course or death (B) according to patients group stratified according to the presence of diabetes mellitus (DM) or fibrosis-4 (FIB-4) index. Data were analyzed using multivariate logistic regression and all data are expressed as OR (95% confidence intervals). Model was adjusted for age, sex, and underlying diseases. HR, hazard ratio.

Fig. 5The estimated mean of duration of confirmation to (A) release and (B) hospital length. Data were analyzed using general linear model and all data are expressed as the mean±standard error. Model was adjusted for age, sex, and underlying diseases. NS, not significant; DM, diabetes mellitus; FIB-4, fibrosis-4. aP<0.01; bP<0.05.