Exemestane: A milestone against breast cancer : Journal of Postgraduate Medicine (original) (raw)

Drug Review

A milestone against breast cancer

Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, India

*Pfizer Limited, Mumbai, India

Correspondence: Sudeep S Acharya, E-mail: [email protected]

Received December 13, 2006

Received in revised form February 01, 2007

Accepted March 05, 2007

Abstract

Rapid advances in the treatment of breast cancer, especially in the form of hormone therapy have truly increased the hope of longer and better disease-free survival for these patients. Exemestane, a third generation aromatase inhibitor has been extensively evaluated in metastatic as well as adjuvant therapy of breast cancer. It has also been evaluated for its safety profile, especially on bone and lipids. Exemestane provides hope to the patients with breast cancer both in early and metastatic disease. This review analyzes all the aspects of exemestane therapy.