PHYSICO-CHEMICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN PRODUCED BY MICROBIAL TRANSFORMATION (original) (raw)

Abstract

By microbial transformation of tylosin (I), the following eight new acyl derivatives were obtained: 3-acetyltylosin (II), 3-propionyltylosin (III), 4''-butyryltylosin (IV), 4''-isovaleryltylosin (V), 3-acetyl-4''-butyryltylosin (VI), 3-acetyl-4''-isovaleryltylosin (VII), 3-propionyl-4''-butyryltylosin (VIII) and 3-propionyl-4''-isovaleryltylosin (IX).