EPOXOMICIN, A NEW ANTITUMOR AGENT OF MICROBIAL ORIGIN (original) (raw)

Abstract

An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-β-aminoketone group, and is closely related to eponemycin.