Myra White | University of Dundee (original) (raw)
Address: Dundee, Dundee City, United Kingdom
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Journal of the American Society of Nephrology
BackgroundVascular calcification, a risk factor for cardiovascular disease, is common among patie... more BackgroundVascular calcification, a risk factor for cardiovascular disease, is common among patients with CKD and is an independent contributor to increased vascular stiffness and vascular risk in this patient group. Vitamin K is a cofactor for proteins involved in prevention of vascular calcification. Whether or not vitamin K supplementation could improve arterial stiffness in patients with CKD is unknown.MethodsTo determine if vitamin K supplementation might improve arterial stiffness in patients in CKD, we conducted a parallel-group, double-blind, randomized trial in participants aged 18 or older with CKD stage 3b or 4 (eGFR 15–45 ml/min per 1.73 m2). We randomly assigned participants to receive 400 μg oral vitamin K2 or matching placebo once daily for a year. The primary outcome was the adjusted between-group difference in carotid-femoral pulse wave velocity at 12 months. Secondary outcomes included augmentation index, abdominal aortic calcification, BP, physical function, and b...
Coronary Health Care, 2000
... ORIGINAL ARTICLE. Uptake and adherence of women post myocardial infarction to phase III cardi... more ... ORIGINAL ARTICLE. Uptake and adherence of women post myocardial infarction to phase III cardiac rehabilitation: are things changing? M. Thow a , P. Isoud b , M. White c , I. Robertson c , E. Keith d and G. Armstrong d. a Department ...
Journal of Advanced Nursing, 2004
Promoting participation in cardiac rehabilitation: patient choices and experiences Background. Ca... more Promoting participation in cardiac rehabilitation: patient choices and experiences Background. Cardiac rehabilitation can be an effective means for the secondary prevention of coronary heart disease, but a majority of eligible individuals fail to attend or drop out prematurely. Little research has examined patients' decisions about attendance. Aims. This paper reports a study examining patients' beliefs and decision-making about cardiac rehabilitation attendance. Methods. A purposive sample of patients from a mixed urban-rural region of Scotland was studied in 2001 using focus groups. Those who were eligible for a standardized 12-week cardiac rehabilitation programme were compared, with separate focus groups held for individuals with high attendance (>60% attendance; n ¼ 27), high rates of attrition (<60% attendance; n ¼ 9) and non-attendance (0% attendance; n ¼ 8). A total of 44 patients (33 men; 11 women) took part in eight focus groups. Results. Participants from all groups held sophisticated and cohesive frameworks of beliefs that influenced their attendance decisions. These beliefs related to the self, coronary heart disease, cardiac rehabilitation, other attending patients, and health professionals' knowledge base. An enduring embarrassment about group or public exercise also influenced attendance. Those who attended reported increased faith in their bodies, a heightened sense of fitness and a willingness to support new patients who attended. Conclusions. Reassurance to ease exercise embarrassment should be given before and during the early stages of programmes, and this could be provided by existing patients. Strategies to promote inclusion should address the inhibiting factors identified in the study, and should present cardiac rehabilitation as a comprehensive programme of activities likely to be of benefit to the individual irrespective of personal characteristics, such as age, sex or exercise capacity.
Journal of the American Society of Nephrology
BackgroundVascular calcification, a risk factor for cardiovascular disease, is common among patie... more BackgroundVascular calcification, a risk factor for cardiovascular disease, is common among patients with CKD and is an independent contributor to increased vascular stiffness and vascular risk in this patient group. Vitamin K is a cofactor for proteins involved in prevention of vascular calcification. Whether or not vitamin K supplementation could improve arterial stiffness in patients with CKD is unknown.MethodsTo determine if vitamin K supplementation might improve arterial stiffness in patients in CKD, we conducted a parallel-group, double-blind, randomized trial in participants aged 18 or older with CKD stage 3b or 4 (eGFR 15–45 ml/min per 1.73 m2). We randomly assigned participants to receive 400 μg oral vitamin K2 or matching placebo once daily for a year. The primary outcome was the adjusted between-group difference in carotid-femoral pulse wave velocity at 12 months. Secondary outcomes included augmentation index, abdominal aortic calcification, BP, physical function, and b...
Coronary Health Care, 2000
... ORIGINAL ARTICLE. Uptake and adherence of women post myocardial infarction to phase III cardi... more ... ORIGINAL ARTICLE. Uptake and adherence of women post myocardial infarction to phase III cardiac rehabilitation: are things changing? M. Thow a , P. Isoud b , M. White c , I. Robertson c , E. Keith d and G. Armstrong d. a Department ...
Journal of Advanced Nursing, 2004
Promoting participation in cardiac rehabilitation: patient choices and experiences Background. Ca... more Promoting participation in cardiac rehabilitation: patient choices and experiences Background. Cardiac rehabilitation can be an effective means for the secondary prevention of coronary heart disease, but a majority of eligible individuals fail to attend or drop out prematurely. Little research has examined patients' decisions about attendance. Aims. This paper reports a study examining patients' beliefs and decision-making about cardiac rehabilitation attendance. Methods. A purposive sample of patients from a mixed urban-rural region of Scotland was studied in 2001 using focus groups. Those who were eligible for a standardized 12-week cardiac rehabilitation programme were compared, with separate focus groups held for individuals with high attendance (>60% attendance; n ¼ 27), high rates of attrition (<60% attendance; n ¼ 9) and non-attendance (0% attendance; n ¼ 8). A total of 44 patients (33 men; 11 women) took part in eight focus groups. Results. Participants from all groups held sophisticated and cohesive frameworks of beliefs that influenced their attendance decisions. These beliefs related to the self, coronary heart disease, cardiac rehabilitation, other attending patients, and health professionals' knowledge base. An enduring embarrassment about group or public exercise also influenced attendance. Those who attended reported increased faith in their bodies, a heightened sense of fitness and a willingness to support new patients who attended. Conclusions. Reassurance to ease exercise embarrassment should be given before and during the early stages of programmes, and this could be provided by existing patients. Strategies to promote inclusion should address the inhibiting factors identified in the study, and should present cardiac rehabilitation as a comprehensive programme of activities likely to be of benefit to the individual irrespective of personal characteristics, such as age, sex or exercise capacity.