Kuntal Bhattacharya | Durgapur Govt. College (original) (raw)

Papers by Kuntal Bhattacharya

Experimental Cell Research, Nov 1, 1963

Abstract A cytochemical technique is established for assessment of succinic dehydrogenase activit... more Abstract A cytochemical technique is established for assessment of succinic dehydrogenase activity separately with Nitro-BT and 2,3,5-triphenyl tetrazolium chloride in different parts of cells, keeping the cellular morphology intact.

Journal of Endocrinology, 1954

SUMMARY 1. When the state of the thyroid is classified as euthyroid or hyperthyroid from a previo... more SUMMARY 1. When the state of the thyroid is classified as euthyroid or hyperthyroid from a previous estimation of clinical symptoms, B.M.R. and plasma-bound iodine concentration (P.B.I.), there is no appreciable overlap in either the maximum uptake, the time to reach the maximum, or in the mean rate of iodine accumulation by the thyroid, during the first 3 hr following oral administration of 100 μc. 131I. 2. The line of demarcation between the hyperthyroid and the euthyroid lies at a maximum uptake of 40% of the administered dose or at a maximum average rate of accumulation of 6%/hr during the first 3 hr. 3. The rate of disappearance of iodine from the blood is not so sharply defined in the two groups. In the euthyroid group it varies from 8 to 19%/hr, while in the hyperthyroid it ranges between 16 and 34%/hr.

International Journal of Radiation Biology, 1959

ABSTRACT Summary (1) A technique has been established for the determination of 32P uptake of the ... more ABSTRACT Summary (1) A technique has been established for the determination of 32P uptake of the average tumour cell. (2) A correlation was observed between nucleolar morphology, mitotic index and 32P uptake of an average tumour cell of a particular type of tumour. (3) All the above factors increased consistently from the benign tumour to adeno-carcinoma which retains some amount of differentiation in the form of persistent acinar space and finally to carcinoma simplex where the differentiation is minimum.

Background: Arch-height estimation though practiced usually in supine posture; is neither correct... more Background: Arch-height estimation though practiced usually in supine posture; is neither correct nor scientific as referred in literature, which favour for standing x-rays or archindex as yardstick. In fact the standing x-rays can be excused for being troublesome in busy OPD, but an ink-footprint on simple graph-sheet can be documented, as it is easier, cheaper and requires almost no machineries and expertisation. Objective: So this study aimed to redefine the interrelationship of the radiological standing arch-heights with the arch-index for correlation and regression so that from the later we can derive the radiographical standing arch-height values indirectly, avoiding the actual maneuver. Methods: The study involved 103 adult subjects attending at a tertiary care hospital of North Bengal. From the standing xrays of foot, the standing navicular, talar heights were measured, and 'normalised' with the foot length. In parallel footprints also been obtained for arch-index. Finally variables analysed by SPSS software. Result: The arch-index showed significant negative correlations and simple linear regressions with standing navicular height, standing talar height as well as standing normalised navicular and talar heights analysed in both sexes separately with supporting mathematical equations. Conclusion: To measure the standing arch-height in a busy OPD, it is wise to have the footprint first. Arch-index once get known, can be put in the equations as derived here, to predict the preferred standing arch-heights in either sex.

Annals of the National Academy of Medical Sciences. India, Nov 13, 2022

한국미생물학회 학술대회논문집, May 1, 2012

Journal of Forestry, 1968

Microbial production of chemicals and fuels has often been cited as the highly viable solution to... more Microbial production of chemicals and fuels has often been cited as the highly viable solution to the current energy crisis. It has also been widely exploited to produce value-added products such as pharmaceuticals, nutraceuticals, food flavorings and fine chemicals. Knowledge gained from genome sequencing and functional annotations, as well as advances in genetic engineering techniques, enable us to re-code the genetic blueprint of a microbial cell to endow them with new functions such as a non-native metabolic pathway that make a specific biochemical. As the cells are often not optimized to synthesize the target product, significant rewiring of their metabolic networks is required to re-apportion carbon flux towards the target product. This should be performed with careful consideration of cellular protein resource allocation as well as energy and redox balance. However, the task is often complicated by the intricate interplay of the cellular gene-protein-reaction network. In this dissertation, we aim to address several challenges in designing and engineering metabolic pathways by combining techniques in computational biology, metabolic engineering, and synthetic biology. Each project relies extensively on optimization-based computational design, from genetic constructs to pathways and finally the entire metabolic network, to achieve the associated metabolic engineering objectives. In Chapter 1, we review the state-of-the-art metabolic engineering and synthetic biology tools for pathway and strain design. These tools lay the foundation for the development of the subsequent chapters, which deal in-depth with specific challenges in metabolic pathway design and strain optimization. One of the key challenges in metabolic engineering is to ensure a consistent supply of cofactor, which is often shared across over 100 reactions in a cell, to the desirable biosynthesis reactions. In Chapter 2, we describe the design and optimization of a synthetic metabolic pathway in E. coli to improve the availability of an essential redox cofactor NADPH. The synthetic metabolic pathway was derived from the highly active Entner-Doudoroff (ED) pathway of another prokaryote Zymomonas mobilis. Upon optimizing the expression of the multi-enzyme pathway, we obtained strains with improved NADPH production when compared to the wild-type strain. In addition to NADPH production, the ED pathway also simultaneously generates pyruvate and glyceraldehydeiv 3-phopshate, which are the precursors for the methylerythritol phosphate (MEP) pathway. As a proof-of-concept, we demonstrated that combination of the synthetic ED pathway and the MEP pathway improved the production of an NADPH-dependent terpenoid by up to 97%. Motivated by the intriguing roles that glycolytic pathways play in a cell and the effects of their perturbation, in Chapter 3, we switch focus to uncover the reason why specific glycolytic pathways prevail in nature despite the presence of alternatives. Although the ED pathway and the Embden-Meyerhof-Parnas (EMP) glycolytic pathways both convert glucose to pyruvate, they take different routes with different intermediates and yield one or two moles of ATP per mole of glucose. Theoretically, one could construct a thermodynamically feasible (i.e., ΔrG° < 0) glucose utilization pathway to pyruvate with up to five moles of ATP production. This raises the question as to why nature preferably employs either EMP or ED glycolysis in spite of the potential availability of pathways with improved energy yield. By computationally designing and assessing over 10,000 possible routes between glucose and pyruvate, we attempt to decipher the designing principles of the natural glycolytic pathways. The computational pipeline developed in this case study for pathway design and analysis can be applied to other important bioconversion pathways. While the earlier chapters delve on the design and optimization of a pathway for redox and energy cofactors supply, generally the entire metabolic network of a microbial cell has to be rewired to drive sufficient carbon flux towards the production pathway and prevent the formation of competing by-products. Using the optimization-based strain design procedure OptForce (in Chapter 4), we combed the entire genome-scale metabolic network to pinpoint genetic interventions including up-regulation, down-regulation and knockout that could lead to the overproduction of the target biochemicals in yeast and cyanobacteria. We further demonstrated that our computational approach not only identified genetic manipulation strategies that recapitulate experimental results but also suggested novel interventions that improve experimental yields. In Chapter 5, we conclude the dissertation by summarizing current metabolic engineering efforts and discussing the remaining challenges as well as our future perspectives on the development of microbial cell factories.

After prolonged use of the synthetic insecticides, novel insecticides of botanical origin are pre... more After prolonged use of the synthetic insecticides, novel insecticides of botanical origin are preferred for environment safety as well as human life. Present study was conducted to evaluate the larvicidal capability of Capparis zeylanica against Culex quinquefasciatus. Crude, cold and hot aqueous and ethyl acetate solvent extracts of foliages of C. zeylanica were tested against all instars larvae of Cx. quinquefasciatus. Lethal concentrations were determined. Effect on the non target water fauna was also tested. Cent percent mortality was found with 0.25% concentration of crude extracts against 1 st and 2 nd instar larvae. No larvicidal responses were found with cold and hot aqueous extracts. Highest mortality was found against 1 st and 2 nd instar larvae at 90 ppm concentration of ethyl acetate extracts at 72 h post exposure. Non-target populations were found non-responsive to active fraction. Secondary metabolites like Tannin, flavonoids and terpenoid were detected through prelimi...

International journal of pharma and bio sciences, 2015

Moringa oleifera (Lam.) is well known for wide range of medicinal activities and contribution to ... more Moringa oleifera (Lam.) is well known for wide range of medicinal activities and contribution to dietary diversity. The present study focused on investigating the antibacterial potentiality of the crude extract and different solvent extracts of the pods of M. oleifera using agar well diffusion method against pathogenic gram negative bacterial strains namely Pseudomonas fluorescens and Pseudomonas putida and gram positive bacterial strains namely Bacillus mycoides and Bacillus licheniformis. The best result was showed by Petroleum ether extract against the said bacteria. M.I.C. of the aforementioned extract on gram negative bacteria P. fluorescens and P. putida were found to be 28.6 µg/ml and 32.0 µg/ml respectively while 39 µg/ml and 42 µg/ml values were obtained for gram positive bacteria B. mycoides and B. licheniformis respectively. The petroleum ether extract of M. oleifera pods may act as a novel and effective antibacterial agent.

International journal of pharma and bio sciences, 2015

Vector control is the foremost step to diminish the mosquito borne diseases as the proper vaccina... more Vector control is the foremost step to diminish the mosquito borne diseases as the proper vaccinations are yet to develop against those obnoxious diseases. After many resistant cases, it is important to develop other sources of eco-friendly insecticides. The present piece of study was designed to evaluate the mosquito larvicidal efficacy of Operculina turpethum against malarial vector Anopheles stephensi. Hot and cold aqueous leaf extracts, and two different solvent extracts were treated against all the larval instars. LC50 and LC90 values were determined. Statistical justifications were made by log-probit, regression and ANOVA analyses. Cent percent mortality was found against 1 st instar larvae at a concentration of 0.5% hot aqueous and 160 ppm solvent extracts after 72 h of exposure. Non-target organisms were nonresponsive after treatment with the same. From the present study it can be concluded that the bioactive fractions from O. turpethum leave extracts have remarkable mosquit...

Indian Pacing and Electrophysiology Journal, 2021

A long VA tachycardia during a typical atrioventricular nodal reentrant tachycardia (AVNRT) can b... more A long VA tachycardia during a typical atrioventricular nodal reentrant tachycardia (AVNRT) can be a concomitant atypical AVNRT, atrial tachycardia or rarely atrio-ventricular reentrant tachycardia (AVRT). There are reported associations of AVNRT with other tachycardia substrates. Maneuvers are useful for differentiating the mechanism of the second tachycardia. Atrial tachycardia (AT) is one common association. When the AT originates from the lower triangle of Koch/near coronary sinus ostium, it can mimic slow-slow/fast-slow AVNRT. We encountered an interesting case where a longer VA tachycardia got reproducibly induced when a critically timed atrial premature depolarisation was delivered on typical AVNRT. It was proved to be an AT. A slow pathway modification in the lower TOK was successful to eliminate both the tachycardia substrate.

Journal of Arrhythmia, 2021

Inadvertent direct atrial capture and pure his capture can result in variable findings during par... more Inadvertent direct atrial capture and pure his capture can result in variable findings during parahis pacing manoeuvre (PHP). Understanding the results and positioning the pacing bipole towards ventricular aspect (distal his region) is helpful to avoid ambiguous results during PHP.

Advances in Nanoscience and Nanotechnology, 2020

Mosquitoes are very obnoxious insects and vectors of many diseases like malaria, filariasis, deng... more Mosquitoes are very obnoxious insects and vectors of many diseases like malaria, filariasis, dengue, yellow fever, encephalitis etc. Among these, malaria is transmitted by Anopheles stephensi mainly in urban areas across the temperate country. So, there is an imperative requirement to imply some mechanisms to reduce the mosquito vector to facilitate the reduction of vector borne diseases throughout the globe. But, mosquito control strategies are now in front of a threat because mosquito populations get resistance against the available synthetic insecticides. Besides the chemical insecticides, several other ways to control the vector population proved unsuccessful in most of the cases. Now, various researchers are trying to develop an alternate effective approach to eradicate malaria from the earth by controlling its vector by using a product which is ecofreindly, cost effective, biodegradable, non-toxic and selective in nature. So, by the amalgamation of the two fields namely the na...

Journal of the American College of Cardiology, 2017

We show that the peculiarities of the electron band structure strongly affect the spin-valve effe... more We show that the peculiarities of the electron band structure strongly affect the spin-valve effect in heterostructures consisting of a superconductor (S) and two ferromagnetic layers F1 and F2. For the S/F1/F2 systems the energy shift between the electron bands in the S and F2 layers determines wether the critical temperature Tc of the superconductor increases or decreases as a function of the angle θ between the magnetic moments in the ferromagnets. In the case of half-metallic F2 layer the type of the spin-valve effect becomes dependent on the position of the only occupied spin-band and the minimum of Tc may correspond to the anti-parallel, parallel or non-collinear orientations of magnetic moments. Also, for the first time, we analytically demonstrate the possibility of the triplet spin-valve effect in the F/S/half-metal structures.

Molecular Entomology, 2016

Isolation and characterization of a soil bacterial strain were done and its dose dependant larvic... more Isolation and characterization of a soil bacterial strain were done and its dose dependant larvicidal efficacy against immatures of Culex quinquefasciatus was evaluated in laboratory and field conditions. N was isolated from soil samples of Burdwan district, West Bengal, India. Morphological, biochemical and physiological characteristics were studied and 16S rDNA gene sequence alignment was done for taxonomic identity of the strain with the establishment of a dendogram. Laboratory bioassays were conducted to evaluate the larvicidal properties with the active formulation. The experiment was further detailed in field conditions to evaluate the larvicidal efficacy of the active formulation with determination of LC50 values and quantification of costing effects on non-target water fauna. 16S r-DNA gene sequence analysis showed that this isolate N belongs to Bacillus cereus. The bioactive formulation of this isolate showed efficient larvicidal activity both in laboratory (LC50=0.45 mg/dl, 0.53 mg/dl, 0.65 mg/dl and 0.76 mg/dl for 1st, 2nd, 3rd and 4th instars larvae respectively) and field conditions. The soil isolated bacterial strain showed potential of a biocontrol agent against mosquito immatures.

Experimental Cell Research, Nov 1, 1963

Abstract A cytochemical technique is established for assessment of succinic dehydrogenase activit... more Abstract A cytochemical technique is established for assessment of succinic dehydrogenase activity separately with Nitro-BT and 2,3,5-triphenyl tetrazolium chloride in different parts of cells, keeping the cellular morphology intact.

Journal of Endocrinology, 1954

SUMMARY 1. When the state of the thyroid is classified as euthyroid or hyperthyroid from a previo... more SUMMARY 1. When the state of the thyroid is classified as euthyroid or hyperthyroid from a previous estimation of clinical symptoms, B.M.R. and plasma-bound iodine concentration (P.B.I.), there is no appreciable overlap in either the maximum uptake, the time to reach the maximum, or in the mean rate of iodine accumulation by the thyroid, during the first 3 hr following oral administration of 100 μc. 131I. 2. The line of demarcation between the hyperthyroid and the euthyroid lies at a maximum uptake of 40% of the administered dose or at a maximum average rate of accumulation of 6%/hr during the first 3 hr. 3. The rate of disappearance of iodine from the blood is not so sharply defined in the two groups. In the euthyroid group it varies from 8 to 19%/hr, while in the hyperthyroid it ranges between 16 and 34%/hr.

International Journal of Radiation Biology, 1959

ABSTRACT Summary (1) A technique has been established for the determination of 32P uptake of the ... more ABSTRACT Summary (1) A technique has been established for the determination of 32P uptake of the average tumour cell. (2) A correlation was observed between nucleolar morphology, mitotic index and 32P uptake of an average tumour cell of a particular type of tumour. (3) All the above factors increased consistently from the benign tumour to adeno-carcinoma which retains some amount of differentiation in the form of persistent acinar space and finally to carcinoma simplex where the differentiation is minimum.

Background: Arch-height estimation though practiced usually in supine posture; is neither correct... more Background: Arch-height estimation though practiced usually in supine posture; is neither correct nor scientific as referred in literature, which favour for standing x-rays or archindex as yardstick. In fact the standing x-rays can be excused for being troublesome in busy OPD, but an ink-footprint on simple graph-sheet can be documented, as it is easier, cheaper and requires almost no machineries and expertisation. Objective: So this study aimed to redefine the interrelationship of the radiological standing arch-heights with the arch-index for correlation and regression so that from the later we can derive the radiographical standing arch-height values indirectly, avoiding the actual maneuver. Methods: The study involved 103 adult subjects attending at a tertiary care hospital of North Bengal. From the standing xrays of foot, the standing navicular, talar heights were measured, and 'normalised' with the foot length. In parallel footprints also been obtained for arch-index. Finally variables analysed by SPSS software. Result: The arch-index showed significant negative correlations and simple linear regressions with standing navicular height, standing talar height as well as standing normalised navicular and talar heights analysed in both sexes separately with supporting mathematical equations. Conclusion: To measure the standing arch-height in a busy OPD, it is wise to have the footprint first. Arch-index once get known, can be put in the equations as derived here, to predict the preferred standing arch-heights in either sex.

Annals of the National Academy of Medical Sciences. India, Nov 13, 2022

한국미생물학회 학술대회논문집, May 1, 2012

Journal of Forestry, 1968

Microbial production of chemicals and fuels has often been cited as the highly viable solution to... more Microbial production of chemicals and fuels has often been cited as the highly viable solution to the current energy crisis. It has also been widely exploited to produce value-added products such as pharmaceuticals, nutraceuticals, food flavorings and fine chemicals. Knowledge gained from genome sequencing and functional annotations, as well as advances in genetic engineering techniques, enable us to re-code the genetic blueprint of a microbial cell to endow them with new functions such as a non-native metabolic pathway that make a specific biochemical. As the cells are often not optimized to synthesize the target product, significant rewiring of their metabolic networks is required to re-apportion carbon flux towards the target product. This should be performed with careful consideration of cellular protein resource allocation as well as energy and redox balance. However, the task is often complicated by the intricate interplay of the cellular gene-protein-reaction network. In this dissertation, we aim to address several challenges in designing and engineering metabolic pathways by combining techniques in computational biology, metabolic engineering, and synthetic biology. Each project relies extensively on optimization-based computational design, from genetic constructs to pathways and finally the entire metabolic network, to achieve the associated metabolic engineering objectives. In Chapter 1, we review the state-of-the-art metabolic engineering and synthetic biology tools for pathway and strain design. These tools lay the foundation for the development of the subsequent chapters, which deal in-depth with specific challenges in metabolic pathway design and strain optimization. One of the key challenges in metabolic engineering is to ensure a consistent supply of cofactor, which is often shared across over 100 reactions in a cell, to the desirable biosynthesis reactions. In Chapter 2, we describe the design and optimization of a synthetic metabolic pathway in E. coli to improve the availability of an essential redox cofactor NADPH. The synthetic metabolic pathway was derived from the highly active Entner-Doudoroff (ED) pathway of another prokaryote Zymomonas mobilis. Upon optimizing the expression of the multi-enzyme pathway, we obtained strains with improved NADPH production when compared to the wild-type strain. In addition to NADPH production, the ED pathway also simultaneously generates pyruvate and glyceraldehydeiv 3-phopshate, which are the precursors for the methylerythritol phosphate (MEP) pathway. As a proof-of-concept, we demonstrated that combination of the synthetic ED pathway and the MEP pathway improved the production of an NADPH-dependent terpenoid by up to 97%. Motivated by the intriguing roles that glycolytic pathways play in a cell and the effects of their perturbation, in Chapter 3, we switch focus to uncover the reason why specific glycolytic pathways prevail in nature despite the presence of alternatives. Although the ED pathway and the Embden-Meyerhof-Parnas (EMP) glycolytic pathways both convert glucose to pyruvate, they take different routes with different intermediates and yield one or two moles of ATP per mole of glucose. Theoretically, one could construct a thermodynamically feasible (i.e., ΔrG° < 0) glucose utilization pathway to pyruvate with up to five moles of ATP production. This raises the question as to why nature preferably employs either EMP or ED glycolysis in spite of the potential availability of pathways with improved energy yield. By computationally designing and assessing over 10,000 possible routes between glucose and pyruvate, we attempt to decipher the designing principles of the natural glycolytic pathways. The computational pipeline developed in this case study for pathway design and analysis can be applied to other important bioconversion pathways. While the earlier chapters delve on the design and optimization of a pathway for redox and energy cofactors supply, generally the entire metabolic network of a microbial cell has to be rewired to drive sufficient carbon flux towards the production pathway and prevent the formation of competing by-products. Using the optimization-based strain design procedure OptForce (in Chapter 4), we combed the entire genome-scale metabolic network to pinpoint genetic interventions including up-regulation, down-regulation and knockout that could lead to the overproduction of the target biochemicals in yeast and cyanobacteria. We further demonstrated that our computational approach not only identified genetic manipulation strategies that recapitulate experimental results but also suggested novel interventions that improve experimental yields. In Chapter 5, we conclude the dissertation by summarizing current metabolic engineering efforts and discussing the remaining challenges as well as our future perspectives on the development of microbial cell factories.

After prolonged use of the synthetic insecticides, novel insecticides of botanical origin are pre... more After prolonged use of the synthetic insecticides, novel insecticides of botanical origin are preferred for environment safety as well as human life. Present study was conducted to evaluate the larvicidal capability of Capparis zeylanica against Culex quinquefasciatus. Crude, cold and hot aqueous and ethyl acetate solvent extracts of foliages of C. zeylanica were tested against all instars larvae of Cx. quinquefasciatus. Lethal concentrations were determined. Effect on the non target water fauna was also tested. Cent percent mortality was found with 0.25% concentration of crude extracts against 1 st and 2 nd instar larvae. No larvicidal responses were found with cold and hot aqueous extracts. Highest mortality was found against 1 st and 2 nd instar larvae at 90 ppm concentration of ethyl acetate extracts at 72 h post exposure. Non-target populations were found non-responsive to active fraction. Secondary metabolites like Tannin, flavonoids and terpenoid were detected through prelimi...

International journal of pharma and bio sciences, 2015

Moringa oleifera (Lam.) is well known for wide range of medicinal activities and contribution to ... more Moringa oleifera (Lam.) is well known for wide range of medicinal activities and contribution to dietary diversity. The present study focused on investigating the antibacterial potentiality of the crude extract and different solvent extracts of the pods of M. oleifera using agar well diffusion method against pathogenic gram negative bacterial strains namely Pseudomonas fluorescens and Pseudomonas putida and gram positive bacterial strains namely Bacillus mycoides and Bacillus licheniformis. The best result was showed by Petroleum ether extract against the said bacteria. M.I.C. of the aforementioned extract on gram negative bacteria P. fluorescens and P. putida were found to be 28.6 µg/ml and 32.0 µg/ml respectively while 39 µg/ml and 42 µg/ml values were obtained for gram positive bacteria B. mycoides and B. licheniformis respectively. The petroleum ether extract of M. oleifera pods may act as a novel and effective antibacterial agent.

International journal of pharma and bio sciences, 2015

Vector control is the foremost step to diminish the mosquito borne diseases as the proper vaccina... more Vector control is the foremost step to diminish the mosquito borne diseases as the proper vaccinations are yet to develop against those obnoxious diseases. After many resistant cases, it is important to develop other sources of eco-friendly insecticides. The present piece of study was designed to evaluate the mosquito larvicidal efficacy of Operculina turpethum against malarial vector Anopheles stephensi. Hot and cold aqueous leaf extracts, and two different solvent extracts were treated against all the larval instars. LC50 and LC90 values were determined. Statistical justifications were made by log-probit, regression and ANOVA analyses. Cent percent mortality was found against 1 st instar larvae at a concentration of 0.5% hot aqueous and 160 ppm solvent extracts after 72 h of exposure. Non-target organisms were nonresponsive after treatment with the same. From the present study it can be concluded that the bioactive fractions from O. turpethum leave extracts have remarkable mosquit...

Indian Pacing and Electrophysiology Journal, 2021

A long VA tachycardia during a typical atrioventricular nodal reentrant tachycardia (AVNRT) can b... more A long VA tachycardia during a typical atrioventricular nodal reentrant tachycardia (AVNRT) can be a concomitant atypical AVNRT, atrial tachycardia or rarely atrio-ventricular reentrant tachycardia (AVRT). There are reported associations of AVNRT with other tachycardia substrates. Maneuvers are useful for differentiating the mechanism of the second tachycardia. Atrial tachycardia (AT) is one common association. When the AT originates from the lower triangle of Koch/near coronary sinus ostium, it can mimic slow-slow/fast-slow AVNRT. We encountered an interesting case where a longer VA tachycardia got reproducibly induced when a critically timed atrial premature depolarisation was delivered on typical AVNRT. It was proved to be an AT. A slow pathway modification in the lower TOK was successful to eliminate both the tachycardia substrate.

Journal of Arrhythmia, 2021

Inadvertent direct atrial capture and pure his capture can result in variable findings during par... more Inadvertent direct atrial capture and pure his capture can result in variable findings during parahis pacing manoeuvre (PHP). Understanding the results and positioning the pacing bipole towards ventricular aspect (distal his region) is helpful to avoid ambiguous results during PHP.

Advances in Nanoscience and Nanotechnology, 2020

Mosquitoes are very obnoxious insects and vectors of many diseases like malaria, filariasis, deng... more Mosquitoes are very obnoxious insects and vectors of many diseases like malaria, filariasis, dengue, yellow fever, encephalitis etc. Among these, malaria is transmitted by Anopheles stephensi mainly in urban areas across the temperate country. So, there is an imperative requirement to imply some mechanisms to reduce the mosquito vector to facilitate the reduction of vector borne diseases throughout the globe. But, mosquito control strategies are now in front of a threat because mosquito populations get resistance against the available synthetic insecticides. Besides the chemical insecticides, several other ways to control the vector population proved unsuccessful in most of the cases. Now, various researchers are trying to develop an alternate effective approach to eradicate malaria from the earth by controlling its vector by using a product which is ecofreindly, cost effective, biodegradable, non-toxic and selective in nature. So, by the amalgamation of the two fields namely the na...

Journal of the American College of Cardiology, 2017

We show that the peculiarities of the electron band structure strongly affect the spin-valve effe... more We show that the peculiarities of the electron band structure strongly affect the spin-valve effect in heterostructures consisting of a superconductor (S) and two ferromagnetic layers F1 and F2. For the S/F1/F2 systems the energy shift between the electron bands in the S and F2 layers determines wether the critical temperature Tc of the superconductor increases or decreases as a function of the angle θ between the magnetic moments in the ferromagnets. In the case of half-metallic F2 layer the type of the spin-valve effect becomes dependent on the position of the only occupied spin-band and the minimum of Tc may correspond to the anti-parallel, parallel or non-collinear orientations of magnetic moments. Also, for the first time, we analytically demonstrate the possibility of the triplet spin-valve effect in the F/S/half-metal structures.

Molecular Entomology, 2016

Isolation and characterization of a soil bacterial strain were done and its dose dependant larvic... more Isolation and characterization of a soil bacterial strain were done and its dose dependant larvicidal efficacy against immatures of Culex quinquefasciatus was evaluated in laboratory and field conditions. N was isolated from soil samples of Burdwan district, West Bengal, India. Morphological, biochemical and physiological characteristics were studied and 16S rDNA gene sequence alignment was done for taxonomic identity of the strain with the establishment of a dendogram. Laboratory bioassays were conducted to evaluate the larvicidal properties with the active formulation. The experiment was further detailed in field conditions to evaluate the larvicidal efficacy of the active formulation with determination of LC50 values and quantification of costing effects on non-target water fauna. 16S r-DNA gene sequence analysis showed that this isolate N belongs to Bacillus cereus. The bioactive formulation of this isolate showed efficient larvicidal activity both in laboratory (LC50=0.45 mg/dl, 0.53 mg/dl, 0.65 mg/dl and 0.76 mg/dl for 1st, 2nd, 3rd and 4th instars larvae respectively) and field conditions. The soil isolated bacterial strain showed potential of a biocontrol agent against mosquito immatures.