Is serum selenium a risk factor for cancer? (original) (raw)

Abstract

A narrow band of counties extending along the southeastern Atlantic coast from Jacksonville, Florida to Charleston, South Carolina were found to have excessively high incidence rates for esophageal cancer in non-white males. White males in the same areas have a 30% higher incidence rate for lung cancer but only average incidence rates were found for non-white males. Selenium is considered to decrease cancer risk in the animal model. In this coastal region, a study of 130 cancer patients who developed a malignancy 2–12 years after baseline examination showed no dose repponse relationship between baseline serum selenium levels and risk of subsequent cancer.

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Authors and Affiliations

  1. Neutron Activation Laboratory, University of Missouri, Columbia, Missouri, U.S.A.
    Steve Morris
  2. Evans Country HDFP Cohort Study for Cancer Incidence Rates, Claxton, Georgia, U.S.A.
    Curtis G. Hames
  3. Evans Country Heart Research Project, 405 E. Long St., 30417, Claxton, GA, U.S.A.
    Ika Peleg & Curtis G. Hames

Authors

  1. Ika Peleg
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  2. Steve Morris
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  3. Curtis G. Hames
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Peleg, I., Morris, S. & Hames, C.G. Is serum selenium a risk factor for cancer?.Med. Oncol. & Tumor Pharmacother. 2, 157–163 (1985). https://doi.org/10.1007/BF02934543

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