Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2 (original) (raw)
Summary
Although herpes simplex virus type 1 (HSV-1) does not induce apoptosis in infected HEp-2 cells, herpes simplex virus type 2 (HSV-2) did induce apoptosis in a small but significant fraction of the same cells. Apoptosis was not observed in Vero or HeLa cells infected with HSV-2. In addition, HSV-2 infection in the presence of cycloheximide induced extensive apoptosis of HEp-2 or HeLa cells.
Access this article
Subscribe and save
- Get 10 units per month
- Download Article/Chapter or eBook
- 1 Unit = 1 Article or 1 Chapter
- Cancel anytime Subscribe now
Buy Now
Price excludes VAT (USA)
Tax calculation will be finalised during checkout.
Instant access to the full article PDF.
Similar content being viewed by others
Author information
Authors and Affiliations
- Department of Virology, School of Medicine, The University of Tokushima, Tokushima, Japan, Japan
A. H. Koyama, H. Akari & A. Adachi - Laboratory of Virology, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan, Japan
F. Goshima & Y. Nishiyama
Authors
- A. H. Koyama
You can also search for this author inPubMed Google Scholar - H. Akari
You can also search for this author inPubMed Google Scholar - A. Adachi
You can also search for this author inPubMed Google Scholar - F. Goshima
You can also search for this author inPubMed Google Scholar - Y. Nishiyama
You can also search for this author inPubMed Google Scholar
Additional information
Received June 9, 1998 Accepted July 15, 1998
Rights and permissions
About this article
Cite this article
Koyama, A., Akari, H., Adachi, A. et al. Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2.Arch. Virol. 143, 2435–2441 (1998). https://doi.org/10.1007/s007050050473
- Published: 16 May 2014
- Issue Date: December 1998
- DOI: https://doi.org/10.1007/s007050050473