Synthesis and antibacterial activity of silver nanoparticles with different sizes (original) (raw)

Abstract

Silver nanoparticles with different sizes (7, 29, and 89 nm mean values) were synthesized using gallic acid in an aqueous chemical reduction method. The nanoparticles were characterized using transmission electron microscopy (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), and ultraviolet–visible (UV–Vis) absorption spectroscopy; the antibacterial activity was assessed using the standard microdilution method, determining the minimum inhibitory concentration (MIC) according to the National Committee for Clinical Laboratory Standards. From the microscopies studies (TEM) we observed that silver nanoparticles have spherical (7 and 29 nm) and pseudospherical shape (89 nm) with a narrow size distribution. The sizes of the silver nanoparticles were controlled by varying some experimental conditions. It was found that the antibacterial activity of the nanoparticles varies when their size diminishes.

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Abbreviations

TEM:

Transmission electron microscopy

DLS:

Dynamic light scattering

XRD:

X-ray diffraction

UV–Vis:

Ultraviolet–visible

MIC:

Minimum inhibitory concentration

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Acknowledgements

This work was partially supported by Fondo de Apoyo a la Investigación (FAI) of Universidad Autónoma de San Luis Potosí (UASLP) and CONACYT-61257. N. Niño-Martínez would like to thank CONACYT for the scholarship No. 185006.

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Authors and Affiliations

1. Maestria en Ciencias Odontológicas, Facultad de Estomatología, UASLP, Av. Manuel Nava 2, Zona Universitaria, San Luis Potosi, SLP, Mexico
   G. A. Martínez-Castañón
2. Instituto de Metalurgia, UASLP, Av. Sierra Leona No. 550, Col. Lomas 2a. Sección, San Luis Potosi, SLP, Mexico
   N. Niño-Martínez
3. Facultad de Ciencias, UASLP, Álvaro Obregón 64, C.P. 78000, San Luis Potosi, SLP, Mexico
   N. Niño-Martínez, J. R. Martínez-Mendoza & Facundo Ruiz
4. Facultad de Ciencias Químicas, UASLP, Álvaro Obregón 64, C.P. 78000, San Luis Potosi, SLP, Mexico
   F. Martínez-Gutierrez

Authors

1. G. A. Martínez-Castañón
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2. N. Niño-Martínez
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3. F. Martínez-Gutierrez
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4. J. R. Martínez-Mendoza
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5. Facundo Ruiz
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Corresponding author

Correspondence toG. A. Martínez-Castañón.

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Martínez-Castañón, G.A., Niño-Martínez, N., Martínez-Gutierrez, F. et al. Synthesis and antibacterial activity of silver nanoparticles with different sizes.J Nanopart Res 10, 1343–1348 (2008). https://doi.org/10.1007/s11051-008-9428-6

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• Received: 29 January 2008
• Accepted: 22 May 2008
• Published: 02 July 2008
• Issue Date: December 2008
• DOI: https://doi.org/10.1007/s11051-008-9428-6

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