Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrus blythi) in Pakistan as confirmed by detection of antigen and antibody (original) (raw)

Abstract

An outbreak resulting in mortality in Sindh Ibex (Capra aegagrus blythi) was investigated. There was a history of about 36 deaths (both young and adult) during the period of 1 month. Disease appeared in a generalized form, affecting the respiratory and digestive systems. Major lesions were respiratory distress, pustules on and in the mouth, ocular–nasal discharges, and severe diarrhea. The most significant lesion was the oculonasal discharges and diarrhea. Deaths were mainly due to blindness, anorexia, diarrhea, and respiratory arrest. Both adult (mortality = 21) and young (mortality = 15) animals were affected with the disease. Peste des petits ruminants virus (PPRV) antigen was detected in the spleen, lung, lymph node, and swab samples by immunocapture enzyme-linked immunosorbent assay. Spleen and lung samples were also tested and found positive for the presence of F-gene of PPRV by polymerase chain reaction. Thirteen of 20 serum samples from nearby sheep and goats were found positive for antibodies to PPRV. The disease threatened the huge population of ibex in the wild life park, which was spread over a large area, but vaccination of the domestic population of sheep and goats in the surrounding villages appeared to control the disease.

Access this article

Log in via an institution

Subscribe and save

• Get 10 units per month
• Download Article/Chapter or eBook
• 1 Unit = 1 Article or 1 Chapter
• Cancel anytime Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

• Abu-Elzein, E. M. E., Housawi, F. M. T., Bashareek, Y., Gameel, A. A., Al-Afaleq A. I., and E. Anderson, 2004. Severe PPR infection in gazelles kept under semi-free range conditions. Journal of Veterinary Medicine-B, 51, 68–71.
  Article Google Scholar
• Anderson, J. and McKay, 1994. The detection of antibodies against PPR virus in cattle, sheep and goats and the possible implications to rinderpest control programme. Epidemiology and Infection. 112, 225–231.
  Article CAS PubMed Google Scholar
• Forsyth, M.A., and Barrett T., 1995. Evaluation of polymerase chain reaction for the detection and characterization of rinderpest and peste des petits ruminants viruses for epidemiological studies. Virus Research, 39(2–3), 151–163.
  Article CAS PubMed Google Scholar
• Govindarajan R, Koteeswaran A, Venugopalan AT, Shyam G, Shaouna S, Shaila MS, Ramachandran S., 1997. Isolation of peste des petits ruminants virus from an outbreak in Indian buffalo (Bubalus bubalis). Veterinary Record, 141, 573–574.
  Article CAS PubMed Google Scholar
• Libeau, G., Diallo, A., Colas, F., Guerre, L., 1994. Rapid differential diagnosis of rinderpest and peste des petitis ruminants using an immunocapture ELISA. Veterinary Record, 134, 300–304.
  Article CAS PubMed Google Scholar

Download references

Acknowledgments

We acknowledge the efforts of Wildlife Department, Sindh; Department of Animal Husbandry, Sindh; and Central Veterinary Diagnostic Laboratory, Tandojam, Sindh for the cooperation in the sampling process.

Author information

Authors and Affiliations

1. National Veterinary Laboratory, Park Road, Islamabad, Pakistan
   Muhammad Abubakar, Zahid Iqbal Rajput, Muhammad Javed Arshed & Qurban Ali
2. Department of Animal Husbandry, Sindh, Pakistan
   Ghulam Sarwar

Authors

1. Muhammad Abubakar
   You can also search for this author inPubMed Google Scholar
2. Zahid Iqbal Rajput
   You can also search for this author inPubMed Google Scholar
3. Muhammad Javed Arshed
   You can also search for this author inPubMed Google Scholar
4. Ghulam Sarwar
   You can also search for this author inPubMed Google Scholar
5. Qurban Ali
   You can also search for this author inPubMed Google Scholar

Corresponding author

Correspondence toMuhammad Abubakar.

Rights and permissions

About this article

Cite this article

Abubakar, M., Rajput, Z.I., Arshed, M.J. et al. Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrus blythi) in Pakistan as confirmed by detection of antigen and antibody.Trop Anim Health Prod 43, 745–747 (2011). https://doi.org/10.1007/s11250-010-9776-y

Download citation

• Accepted: 27 December 2010
• Published: 09 January 2011
• Issue Date: April 2011
• DOI: https://doi.org/10.1007/s11250-010-9776-y

Keywords